A Study for the Seroprevalence of Hepatitis-C Among Healthy Blood Donors, Patients Suffering from Chronic Liver Disease and High Risk Subjects
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 4
Abstract
Aims and Objectives: To study the prevalence of hepatitis C virus (HCV) among healthy blood donors and in patients suffering from chronic liver disease and high risk subjects. Materials and Methods: The study was conducted at the blood bank of SMS Hospital, Jaipur. The blood samples from following 1200 individuals were collected, 1000 consecutive healthy donors, 50 patients suffering from chronic liver disease, attend outpatient door (OPD) and indoor, cases of high risk subjects including 50 thalassaemia patients, 50 patients in haemodialysis units and 50 laboratory workers. These subjects were screened for hepatitis C virus by 3rd generation ELISA method. Results: 1000 consecutive healthy blood donors were tested for anti HCV by third generation ELISA test. 200 high risk subjects including 50 cases of chronic liver disease, 50 cases of thalassaemia, 50 cases in dialysis unit and 50 laboratory workers were screened for anti HCV antibodies. Samples were collected at 0, 1, 3, 6 and 12 month interval. Most of the donors were replacement donors (92%) and majority of whose were male (99.5%). Present study showed prevalence of anti-HCV antibodies 0.4 % in healthy blood donors, 4% in chronic liver disease patient, 4% in thalassaemic patient, 2% in patients on dialysis. Conclusion: The risk of HCV transmission by transfusion has been decrease by routine screening of donated blood along with donor screening and rejection of donor with high risk factor.
Authors and Affiliations
Pramendra Pachori, Saroj Pachori, Geeta Pachori, Aditi Sirohi
Keywords
Related Articles
- EP ID EP535428
- DOI 10.21276/ijmrp.2018.4.4.052
- Views 85
- Downloads 0
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