A STUDY OF DYSLIPIDAEMIA IN LICHEN PLANUS PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 42
Abstract
BACKGROUND Lichen planus (LP) is a distinct autoimmune inflammatory, papulosquamous skin disorder. Some studies have showed an increased prevalence of dyslipidaemia in lichen planus patients. Disturbances in the lipid metabolism due to underlying inflammation and oxidative stress which releases inflammatory cytokines could be accountable for this. Aim of the study was to find out the proportion of dyslipidaemia among lichen planus patients and compare the clinical pattern of lichen planus in patients having dyslipidaemia. MATERIALS AND METHODS This cross-sectional descriptive study was done on 75 lichen planus patients who attended a tertiary care hospital in Kerala. The diagnosis of LP was made by clinical examination and confirmed histopathologically in doubtful cases. Fasting serum was analysed for cholesterol, triglycerides (TG), high density lipoprotein (HDL) and low-density lipoprotein (LDL). The presence of dyslipidaemia was established, based on the National Cholesterol Education Programme Adult Treatment Panel III definitions (NCEP-ATP III criteria). RESULTS The study showed that the proportion of dyslipidaemia in lichen planus was 41.3% and patients with extensive skin lesions showed higher prevalence of dyslipidaemia. CONCLUSION This study demonstrated that a significant proportion of lichen planus patients showed high lipid levels in blood and for patients presenting with LP, physicians should consider screening them for dyslipidaemia.
Authors and Affiliations
Sudhesan Athira, Anitha Krishna
Keywords
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- EP ID EP214048
- DOI 10.14260/Jemds/2017/712
- Views 72
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