A Study of Occurrence of Frailty in Patients of Chronic Obstructive Pulmonary Disease and its Correlation with the Cognitive Function as Assessed by Montreal Cognitive Assessment Score
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 8
Abstract
Introduction: With increasing life expectancy the diseases of elderly age group such as COPD and frailty are more common nowadays than before. COPD is closely related with frailty with shares common risk factors such as smoking, aging, common mechanism of deregulated inflammation, and endocrine dysfunction. Frailty can be defined as a biological syndrome in which a progressive cumulative decline in the reserve capacity of multiple physiological systems illicit an abnormal vulnerability to normal strainers. It is defined as fried phenotype, meeting three or more of five established criteria. Aim of this Study: To find out the occurrence of frailty in patients of COPD and find out correlation of frailty with cognitive impairment in patients with COPD if any. Materials and Methods: In this one point observational study conducted in chest OPD of UCMS and associated hospital, Delhi. Diagnosis of COPD was made using GOLD 2016 guidelines. Frailty was defined on the basis of Fried criteria. MOCA test (Hindi version) was applied for assessment of cognitive function. Study Duration: The study duration was a August 2016-July 2017. Sample size: In this study, 80 patients who satisfying the criteria were enrolled. Result: Out of 80 patients, 61 were males and rests were females. Among them, 63 (78%) patients had diagnosis of frailty. The mean age among frail group was 62.29 ± 10.06 and among non-frail was 51.82 ± 10.98 years. Out of 63 patients with frailty only 3 (4.7%) has MOCA score ≥26 (i.e., normal) and around 17 patients of COPD without frailty only 1 (5.8%) has MOCA score ≥26. Remaining have MOCA score <26, which can be interpreted as the presence of cognitive impairment. P value of this data comes out to be 1.00 which is statistically not significant. Conclusion: Frailty is a common occurrence in COPD patients, but for correlating with cognitive impairment larger sample size is needed.
Authors and Affiliations
Amit Kumar Verma, Dhirendra Kumar Singh
Keywords
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