“A Study of Prevalence of Vitamin D Deficiency in Pregnant Women Attending Antenatal OPD at BHMRC”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 11
Abstract
Background and purpose: For the past few years various observational and interventional trials have been conducted all over the world regarding health implication of vitamin D status and their supplementation. Through this study we plan to look for the prevalence of vitamin D deficiency in pregnant women in Indian scenario and maternal and fetal outcome in pregnant women with vitamin D deficiency. Method: The present study was conducted in the Department of Obstetrics and Gynaecology, Batra Hospital and Medical Research centre, New Delhi from 1st January 2013 to 31st December 2013. A total of 100 subjects were recruited in this study, 50 booked patients and 50 unbooked patients. All subjects were evaluated on the basis of predesigned and pretested proforma with respect to history, clinical examination and ultrasonography. Serum samples of all subjects were taken for assessment of vitamin D levels.. Results: A total of 40% patients had severe vitamin D deficiency, 34% amongst booked and 46% amongst unbooked patients. 15.85% of vitamin D deficient patients developed gestational hypertension while only 11.11% of vitamin D sufficient patients, 20.73% of Vitamin D deficient females developed GDM while only 5.56% patients with normal vitamin D levels. 4.88% of vitamin D deficient females developed PPROM while none of the females with normal vitamin D levels developed PPROM, while Overall 40% newborns had severe vitamin D deficiency at birth, 32% of newborns of booked patients and 48% of newborns of unbooked patients had severe vitamin D deficiency. 32.92% newborns of vitamin D deficient females were LBW while only 16.67% newborns of females with normal vitamin D levels were LBW. A higher incidence of LBW was observed in females with severe vitamin D deficiency (47.5%) compared with mild to moderate deficiency (19.04%).A higher incidence of SGA was observed in females with severe vitamin D deficiency (27.5%) compared with mild to moderate deficiency (15.16%). Interpretation :The present study supports the paradox of prevalent vitamin D deficiency in Indian pregnant women despite abundant sunshine. This study concludes that severe vitamin D deficiency is a risk factor for adverse pregnancy outcome (gestational hypertension, gestational diabetes mellitus and fetal growth restriction) and also supports that vitamin D supplementation during antenatal period improves neonatal vitamin D status as well as fetal outcomes
Authors and Affiliations
Jyoti Sharma, Mehrotra Swati, Dahiya Deepti, Arora Manjeet
Keywords
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- EP ID EP249546
- DOI 10.9790/0853-1611103337
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