Advances in functional magnetic resonance imaging for assessing brain function changes in depression psychotherapy
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 6
Abstract
Psychotherapy is one of the widely used therapies for depression. Yet there are currently no definitive biological markers as indicators of effectiveness. Using functional magnetic resonance imaging (fMRI) to assess the neuroimaging biomarkers before and after different psychological treatments for depression reveals corresponding changes in brain region activation and functional connectivity. For example, after cognitive-behavioral therapy, the prefrontal cortex of patients may be activated and dynamic functional connectivity variability may change, while mindfulness therapy may show alterations in specific temporal lobe regions. Additionally, studies exploring special populations and internet-based psychological intervention have also found changes in brain region activation and functional connectivity, providing guidance for the efficacy evaluation of corresponding psychotherapies. This article reviews the characteristic brain region or network changes in fMRI activity after different psychotherapies in depressed patients, aiming to discuss future directions for research that integrates neuroimaging with psychological treatment for depression.
Authors and Affiliations
ZHANG Yunyan,XIA Xiaodi,ZHANG Tanwei,ZHOU Ying,WEN Keyi,WANG Fangyi,FU Yixiao,
Keywords
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