Analysis of the evolution of the residual risk of HIV transmission at the National Blood Transfusion Center (CNTS) of Lomé (Togo) from January 2008 to December 2012
Journal Title: International Journal of Blood Transfusion and Immunohematology - Year 2015, Vol 5, Issue 2
Abstract
Aims: This study aimed to: - Analyze the HIV residual risk of transfusion at the CNTS of Lomé from January 2008 to December 2012 - Indicate future directions to strengthen blood safety. Methods: The residual risk of HIV transmission by blood transfusion has been estimated by the indirect method proposed by SCHREIBER. This method estimates the risk that a donation was made during the immunologically silent period. Using the incident cases, we calculated the incidence rates of HIV that multiplied by the duration of the serological window period gave the residual risk of transmission. Results: Blood donors included in study were a total of 16, 042 over the five years. Males accounted for 79. 37% and 64. 41% of donors were under 30 years. The number of cases of confirmed HIV was zero in 2008, five in 2009, five in 2010, three in 2011, two in 2012. The residual risk (RR) was respectively 1/17391 in 2009, 1/19342 in 2010, 1/43478 in 2011 and 1/181818 in 2012. From 2009 to 2012, the RR decreased by 10.45 times. Conclusion: The residual risk was relatively high in 2009 but has gradually declined over ten times in 2012. A policy of blood donators and the orientation of the CNTS towards new technologies such as the inactivation of the pathogens might contribute to reduce appreciably the RR of diseases transmitted by the blood.
Authors and Affiliations
Liza Koboyo Nadjir, Akuété Yvon Segbena, Jean-Pierre Cazenave
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