ANTIBIOTIC RESISTANCE PATTERN OF BLOODSTREAM BACTERIAL ISOLATES FROM ENTERIC FEVER PATIENTS: A PROSPECTIVE CROSS-SECTIONAL STUDY
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2017, Vol 6, Issue 2
Abstract
Background:Enteric fever continues to remain a major public health problem, especially in regions of South-East Asia due to poor sanitation and personal hygiene. Bangladesh open prone to enteric fever outbreaks and is an endemic region of typhoid fever. Enteric fever caused by Salmonella typhi has not yet been adequately explored in this region. The emergence of antimicrobial resistance has complicated the treatment and management of enteric fever.Aims:To describe the pattern of bacterial isolates from the blood cultures and determine their antibiotic resistance in cases of bacteremia due to enteric fever. Methodology: This was a laboratory based prospective cross sectional study. A total of 62 isolates of Salmonella typhi&Salmonella paratyphi were found in the blood C/S report. Blood cultures were performed to isolate bacteria and susceptibility to antibiotics was assessed as per standard procedures of microbiological methods. The data was analyzed using SPSS for windows version 22.0 software.Results: Among the total isolates studied, 20% was S. typhi were found multidrug resistant (defined as resistance to ampicillin, chloramphenicol and cotrimoxazole). There was a decrease in the susceptibility to ciprofloxacin and azithromycin. Ceftriaxone and cefixime showed 100 % sensitivity. Conclusion:MDR Salmonella typhi continues to be important public health issue. Presence ciprofloxacin and azithromycin resistance is a concern and requires further study.
Authors and Affiliations
MOHAMMAD MORSHAD ALAM*| PG STUDENT, DEPARTMENT OF PUBLIC HEALTH, NORTH SOUTH UNIVERSITY, SHAJEDA AKTER NISHAT| PG STUDENT, DEPARTMENT OF MICROBIOLOGY, NOAKHALI SCIENCE AND TECHNOLOGY UNIVERSITY Noakhali Science and Technology University, Sonapur, Noakhali - 3814, Bangladesh, ABRAR WAHAB| PG STUDENT, DEPARTMENT OF PUBLIC HEALTH, NORTH SOUTH UNIVERSITY, ABDUL HALIM| PG STUDENT, DEPARTMENT OF MICROBIOLOGY, NOAKHALI SCIENCE AND TECHNOLOGY UNIVERSITY Noakhali Science and Technology University, Sonapur, Noakhali - 3814, Bangladesh
Keywords
Related Articles
- EP ID EP3844
- DOI -
- Views 463
- Downloads 21
Microbiological profile and antibiotic susceptibility pattern of uropathogens in Anand district of Gujarat, India.
Background: Antimirobial drug resistance in urinary tract pathogens is a challenging problem to the medical practitioners & important reason for increased morbidity and healthcare expenditure. Aim/Objective: To document...
EXPLORATION OF MUCIN PROTEIN FROM MACROCHLYMUS INDICA AND DETERMINED ITS IMMUNOGENICITY STUDIES
Introduction – Mucins are included under the category of high molecular weight (i.e. O-glycosylated) proteins which plays a crucial role with respect to protection, lubrication and acid resistance of the epithelial cell...
EFFECT OF MOMORDICA CHARANTIA L. SEEDS EXTRACT ON BIOPHYSICAL AND BIOCHEMICAL PARAMETERS OF WOUND IN EXPERIMENTALLY INDUCED DIABETES IN RATS
Momordica charantia Linn. seed extrat in the form of an ointment (20% w/w dried powder in simple ointment base) was evaluated for wound-healing potential in an excision wound model whereas the the seed extract given or...
IMMUNOHISTOCHEMICAL CORRELATION OF E-CADHERIN EXPRESSION WITH DIFFERENTIATION GRADE OF INVASIVE DUCTAL CARCINOMA IN SUDANESE FEMALES
Background: E-cadherin is a cell surface protein involved in cell adhesion, present in normal breast epithelium, and in certain breast carcinoma. The utility of the E-cadherin immunohistochemical stain to distinguish bet...
DETECTION OF EPSTEIN - BARR VIRUS IN LYMPHOMA LESIONS AMONG SUDANESE PATIENTS USING LMP-1 MONOCLONAL ANTIBODY
OBJECTIVE: this was a retrospective descriptive study aimed to investigate the association of EBV with different types of lymphoma in Sudanese patients. METHODS: Fifty paraffin-embedded formalin-fixed tissue sections of...