ANTIHYPERLIPIDEMIC ACTIVITY OF DIVYA METHIPACHAK AGAINST TRITON X-100 INDUCED HYPERLIPIDEMIA IN RATS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 8
Abstract
The present study was designed to evaluate the anti-hyperlipidemic activity of Divya Methipachak a polyherbal formulation against triton induced hyperlipidemia in rats. Hyperlipidemia was induced by Triton X-100 (100 mg/kg, i.p.) and then treated with Atorvastatin (10 mg/kg, p.o) and low and high dose of Divya Methipachak (150 mg/kg and 300 mg/kg, p.o) for 7 days. The effect of treatment was analyzed by quantification of serum lipid profile, blood glucose level and histopathological analysis. The experimental results indicated all the lipid profile such as total cholesterol, Triglyceride, High density lipoprotein cholesterol, Low density lipoprotein cholesterol and the glucose level were restored significantly by all the treated groups compared to triton group. To conclude Divya Methipachak was found to be potential antihyperlipidemic agent in a dose dependent manner in alleviating abnormal conditions induced by triton.
Authors and Affiliations
Seema Setty , Jignasa Patel , Manodeep Chakraborty , Jagadish Kamath
Keywords
Related Articles
- EP ID EP119763
- DOI -
- Views 81
- Downloads 0
NON INVASIVE THERAPEUTIC DRUG MONITORING OF PROPRANOLOL HYDROCHLORIDE BY REVERSE IONTOPHORESIS
Therapeutic drug monitoring (TDM) is highly required for drugs possessing narrow therapeutic index as a slight variation in the therapeutic range could result in no or low clinical efficiency or causes significant side e...
IN VITRO ANTIBACTERIAL ACTIVITIES STUDY OF POLYMERIC CIPROFLOXACIN SUSPENSIONS
To study the in vitro antibacterial activities of mucoadhesive suspensions containing Ciprofloxacin, three different formulations were prepared by using three polymers, such as Hydroxypropyl methylcellulose (HPMC) (S1),...
CURRENT STATUS AND FUTURE DIRECTIONS OF NEW DRUG DELIVERY TECHNOLOGIES
New drug delivery systems based products have significantly increased in the past few years, and this growth is expected to continue in the near future. Today a large number of companies are busy developing protein- and...
FEED FORMULATION AND FEEDING TECHNOLOGY FOR FISHES
Most fish farmers and ornamental fish hobbyists buy the bulk of their feed from commercial manufacturers. However, small quantities of specialized feeds are often needed for experimental purposes, feeding difficult-to ma...
HERBAL INDICATORS AS AN UPCOMING TREND IN TITREMETRIC ANALYSIS
Indicators are very special chemicals, they will change color of the solution with change in pH by adding acid or alkali. Red cabbage is actually blue in color. It will be quite blue when slice it up and add some tap wat...