ANTIPROLIFERATIVE ACTIVITY OF ETHANOLIC FLOWER EXTRACT FROM NYMPHAEA PUBESCENS WILLD AGAINST HUMAN CERVICAL AND BREAST CARCINOMA IN VITRO
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 1
Abstract
Nymphaea pubescens Willd (Nymphaeaceae) is a fascinating aquatic plant mentioned in siddha system of medicine, in the treatment of bleeding piles, diabetes and as cardiotonic in palpitation of the heart. Nymphaea species was traditionally used for treating cancer. The present study was designed to evaluate the invitro antiproliferative activity of Nymphaea pubescens Willd. The ethanolic extract of different parts such as rhizome, leaf, flower and fruit was subjected for MTT assay. The ethanolic extract of flower part was found to be cytotoxic against human cervical carcinoma Hela cell lines and human breast carcinoma MCF cell lines. The IC50 value of ethanolic flower extract was 91.57µg/ml against Hela cell lines and 99.6µg/ml against MCF-7 cell lines. Significant results were observed thereby justifying the use of plant in the traditional system of medicine.
Authors and Affiliations
E Selvakumari , S Shantha , T Prabhu , C Sreenathkumar
Keywords
Related Articles
- EP ID EP155888
- DOI -
- Views 89
- Downloads 0
A REVIEW ON PATHOPHYSIOLOGY, CLASSIFICATION AND LONG TERM COURSE OF DEPRESSION
Depression is an etiologically heterogeneous group of brain disorders characterized by a wide range of symptoms that reflect alterations in cognitive, psychomotor and emotional processes. Depression is a common problem a...
EVALUATION OF TOTAL ECONOMIC VALUE OF AYURVEDA MEDICINE WITH REFERENCE TO ENVIRONMENTAL VALUATION TECHNIQUES
Ayurveda is one of the oldest medical systems in the world. Health is a state of equilibrium of Physical, Psychological and Spiritual components. This equilibrium is maintained between internal and external environment w...
BIOLOGICAL ACTIVITIES OF 1, 3, 4-OXADIAZOLE: A REVIEW
Oxadiazole, a heterocyclic nucleus has attracted a wide attention of the chemist in search for the new therapeutic molecules. Out of its four possible isomers, 1, 3, 4-oxadiazole is widely exploited for various applicati...
EVALUATION OF ANTI-NOCICEPTIVE AND ANTI-INFLAMMATORY ACTIVITY OF PUNICA GRANATUM SEED EXTRACT
The plant Punica granatum of family Punicaceae is distributed throughout India and reputed to have numerous applications in traditional medicine system. In order to justify its folkloric use in nociception and inflammati...
A NOVEL EXPLORING APPROACH OF CANCER CHEMOTHERAPY BY MULTIPLE EMULSION SYSTEM
Cancer is a disease characterized by uncontrolled multiplication and spread of abnormal forms of the body's own cells, leading cause of death worldwide, accounting for 7.6 million deaths (around 13% of all deaths) in 200...