ANTIMICROBIAL ACTIVITY OF SOME THAI AROMATIC PLANTS AGAINST ORAL PATHOGENS INDUCING HALITOSIS
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 1
Abstract
Objective: The objective of the present work is to analyze that the extracts of 25 Thai aromatic plants used in Thai food recipes were subjected to evaluated antimicrobial activity against Fusobacterium nucleatum and Streptococcus mutans which have been known as bacterial inducing halitosis.Methods: Disk diffusion method, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) by broth microdilution were used to determine the antibacterial activity.Results: The results revealed that three plant extracts, namely Piper betle Linn., Eupatorium stoechadosmum Hance, and Alpinia galangal (L.) Wild can inhibit the growth of both halitosis inducing bacteria with strong activity. Among these, the extract of P. betle Linn. is the most effective in inhibiting both bacteria followed by E. stoechadosmum Hance and A. galangal (L.) Wild, respectively. The MIC (mg/ml) values of the extracts which can inhibit F. nucleatum were ranging from 1.56 to 12.50, and the MBCs (mg/ml) values were ranging from 3.125 to 25.00. In addition, the MICs and MBCs of the extracts which can inhibit S. mutans were found that 1.56–25.00 and 3.125–50.00, respectively.Conclusion: The extracts obtained from P. betle, A. galangal, and E. stoechadosmum displayed good activity against F. nucleatum and S. mutans and these extracts could be a potential source of new antimicrobial agents.
Authors and Affiliations
Plernpit Yasin, Phenphicha Wanachantararuk, Jidaphatinoi Jidaphatinoi, Kanchana Dumri
Keywords
Related Articles
- EP ID EP607183
- DOI 10.22159/ajpcr.2019.v12i1.28404
- Views 105
- Downloads 0
THE EFFECT OF ADMINISTRATION OF AN EQUAL DOSE OF DIFFERENT CLASSES OF PHYTOCHEMICALS ON HEME OXYGENASE-1 GENE AND PROTEIN EXPRESSION IN MICE LIVER
Objective: Heme oxygenase-1 (HO-1) is enzyme that possesses antioxidant, anti-inflammatory, and cytoprotective functions. Induction of HO-1 occurs as an adaptive and beneficial response to various injurious stimuli such...
ANTIMICROBIAL INVESTIGATION AND BINDING MODE ANALYSIS OF SOME NEWLY SYNTHESIZED 4-AMINO-5-((ARYL SUBSTITUTED)-4H-1, 2, 4-TRIAZOLE-3-YL)-THIO LINKED HYDROXAMIC ACID DERIVATIVES
Objective: A series of 5-substituted-4-amino-1, 2, 4-triazole-linked hydroxamic acid derivatives have been synthesized and explored in vitro to evaluate antibacterial and antifungal activities. Methods: Different 5-phen...
CYTOTOXIC EFFECT OF PEPTIDE FUNCTIONALIZED SILVER NANOPARTICLES SYNTHESIZED FROM ALOIN ON BREAST CANCER CELL LINE
Objective: The aim of the present study is to synthesize the silver (Ag) nanoparticle using Aloin with a focus on its antibacterial, antioxidant, and anticancer activity. Methods: The silver nanoparticles were synthesiz...
CYTOTOXIC ACTIVITY OF A MEDICINAL MANGROVE PLANT CERIOPS DECANDRA (GRIFF.) DING HOU LEAVES ON HUMAN BREAST ADENOCARCINOMA CELL LINE MCF-7
Objective: Ceriops decandra (Griff.) Ding Hou (Rhizophoraceae) is an evergreen mangrove tree widely used in folklore medicine for the treatment of several diseases. Concerning the presence of anticancer molecule in C. de...
EVALUATING THE BEST POLYETHYLENE GLYCOL AS SOLID DISPERSION CARRIER BY TAKING ETORICOXIB AS A MODEL DRUG
Objective: The main objective of the current research is focused in discovering the best polyethylene glycol (PEG) as solid dispersion carrier using etoricoxib (ECB) as a model drug. Methods: Varieties of PEG, namely PE...