Antimicrobial Effect of Chromolaena Odorata (L.) and Vernonia Amygdalina Del Leaf Extract on Clinical Isolates from Infected Wound
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 3
Abstract
Herbal medicines has been widely used and forms an integral parts of primary health care in most developing countries today due to its effectiveness, availability and low cost. In the present study, the antimicrobial effect of the leaf extract of Chromolaena odorata (L.) King and Robinson and Vernonia amygdalina Del., (African bitter leaf) was investigated on clinical isolates from infected wound samples. The result revealed that the plant were effective in inhibiting the growth of the test organism (Staphylococcus, E. coli, Pseudomonas and Candida) from the wound samples. The plant extract showed varying zones of inhibitions ranging from 18.9 and 16.2mm for Chromolaena odorata (L.) and Vernonia amygdalina Del. Respectively for Staphylococcus spp, 14.2 and 12.8mm, for E. coli, 20.1 and 16.3mm for Pseudomonas spp and 12.9 and 10.6mm for Candida spp. respectively at 100 percent concentration. Both plant showed an MIC at 25 % except for Candida spp. which showed an MIC at 50 %. respectively for both plant. Research has shown that these plants contains various phytochemical constituents at various concentrations which may be responsible for their antimicrobial properties. The present study therefore reveals the medicinal importance of these plants as used traditionally for the treatment of various ailments.
Authors and Affiliations
Ekaiko, M . U1*,, Ajuga, M. U, Okeke, I. M, Arinze A. G, Ndulaka J. C2
Keywords
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