Bactericidal activity of Flavonoids isolated from Muntingia calabura
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 3
Abstract
The investigation was carried out for the isolation and characterization of the compounds from heart wood of root and root bark of Muntingia calabura. We have isolated six compounds; three from each extract were identified as flavonoids. The bactericidal activity of these compounds found significant against tested bacterial strains (gram-positive and gram-negative). Among the tested compounds, 8-methoxy, 3ʹ,5ʹ7ʹ-trihydroxyflavone and 3,5,7-trihydroxyflavone (Galangin) showed paramount activity against Methicillin-resistant Staphylococcus aureus (MRSA). The results were compared with known standards gentamycin sulphate and cefixime.
Authors and Affiliations
Srinivas Gorripati, Konka Rajashekar, Deepa Dasu, Anvesh Jupaka, Murali Krishna Thupurani
Keywords
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- EP ID EP670940
- DOI 10.21276/ijlssr.2018.4.3.14
- Views 90
- Downloads 0
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