Bactericidal activity of Flavonoids isolated from Muntingia calabura
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 3
Abstract
The investigation was carried out for the isolation and characterization of the compounds from heart wood of root and root bark of Muntingia calabura. We have isolated six compounds; three from each extract were identified as flavonoids. The bactericidal activity of these compounds found significant against tested bacterial strains (gram-positive and gram-negative). Among the tested compounds, 8-methoxy, 3ʹ,5ʹ7ʹ-trihydroxyflavone and 3,5,7-trihydroxyflavone (Galangin) showed paramount activity against Methicillin-resistant Staphylococcus aureus (MRSA). The results were compared with known standards gentamycin sulphate and cefixime.
Authors and Affiliations
Srinivas Gorripati, Konka Rajashekar, Deepa Dasu, Anvesh Jupaka, Murali Krishna Thupurani
Keywords
Related Articles
- EP ID EP670940
- DOI 10.21276/ijlssr.2018.4.3.14
- Views 86
- Downloads 0
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