Change in Alkaline Phosphatase Activity Induced By Tetracycline in Freshwater Mussel, Parreysia cylindrica (Annandale and Prashad)
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 3
Abstract
Alkaline phosphatase is a non-specific hydrolase enzyme. This enzyme is responsible for transphosphorylation and has an important role in the general energetics of an organism. Internal milieu of the organ can be assessed by alteration in the enzymatic activity as it is a tool to indicate the stress offered by various chemical compounds. In the present study, Alkaline phosphatase activity is measured in a fresh water mussel Parreysia cylindrica after acute and chronic exposure to tetracycline, one of the broad spectrum antibiotics. P. cylindrica are exposed to LC50/2 (166.54PPM) for acute treatment upto 96 hrs and LC50/10 (33.30 PPM) for chronic treatment upto 21 days in gills, mantle and digestive gland. In tetracycline exposed bivalves, alkaline phosphatase activity was greatly increased in gills (+26.37%) than mantle and digestive gland while after chronic exposure it showed 25.32% increase upto 14th day and then reached to 16.55% increase upto 21st day in gills over control. The digestive gland showed least increase in alkaline phosphatase activity.
Authors and Affiliations
H. P. Nandurkar
Keywords
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- EP ID EP389797
- DOI 10.9790/3008-1203069294
- Views 83
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