Changing trend in antibiotic sensitivity and resistance patterns of Pseudomonas aeruginosa isolated from pus at a tertiary care hospital in Bhavnagar: A retrospective observational study
Journal Title: Pathology And Laboratory Medicine - Year 2018, Vol 9, Issue 2
Abstract
Pseudomonas aeruginosa is a gram negative rod. It contributes primarily to nosocomial infections. It had many inherent antimicrobial resistance mechanisms. We have limited antibiotic therapeutic options due to the acquisition of resistance mechanisms to antibiotic by this pathogen. This is because of indiscriminate use of antibiotics, failure to complete therapeutic regimens, variations in doses administered and along with over the counter easy availability of antibiotics. Our present study focuses on the prevalence and the change in trend in sensitivity-resistance pattern of P. aeruginosa to antibiotics. In this study, total 2989 pus samples were collected and P.aeruginosa was isolated in 323 samples. After isolation of P.aeruginosa, antibiotic sensitivity testing was performed and analysed by CLSIguideines.Out of these total 323 isolated P. aeruginosa, 182 P. aeruginosa was isolated between July 2015 to Dec 2015 and 141 P.aeruginosa was isolated between Jan 2016 to June 2016. We compare the susceptibility pattern of these two groups of P.aeruginosa to different antibiotics and found that there is decrease in susceptibility of P.aeruginosa to floroquinolone, cephalosporin, and aminoglycosides. There is no change in sensitivity to piperacillin-tazobactam, aztreonam, meropenem, and ceftriaxone-salbactam between these two groups of P.aeruginosa.
Authors and Affiliations
Meghana Chauhan, Saklain Malek, Beena P. Jagad, Kairavi Desai
Keywords
Related Articles
- EP ID EP516456
- DOI -
- Views 59
- Downloads 0
Prevalence of Parasitic infestations in school going children
Introduction and Aim : Over two billion people worldwide are affected by intestinal protozoa and helminths. Intestinal helminthic infestations are most common among school-age children and tend to be of high intensity in...
A case of gliosarcoma: what is new?
Gliosarcoma is a rare biphasic subtype of glioblastoma, with alternating glial and mesenchymal differentiation. It is highly malignant WHO grade IV tumour with poor prognosis. It resembles meningioma radiologically due t...
Suspected Anti-G antibody in pregnant women: Report of two cases
Introduction : Anti-G is one of the cause of Hemolytic Disease of the Fetus and Newborn (HDFN), either alone or in association with anti-C, anti-D or both. The antibody mimics a pattern of anti-C & anti-D reactivity in i...
Changing trend in antibiotic sensitivity and resistance patterns of Pseudomonas aeruginosa isolated from pus at a tertiary care hospital in Bhavnagar: A retrospective observational study
Pseudomonas aeruginosa is a gram negative rod. It contributes primarily to nosocomial infections. It had many inherent antimicrobial resistance mechanisms. We have limited antibiotic therapeutic options due to the acquis...
ABO and Rh-D blood group frequency in a tertiary care hospital at Rajkot - A two year study (January 2016- December 2017)
Background : The ABO and Rhesus (Rh) blood group systems are important for transfusion of blood and its components, organ transplantation, genetic studies and in medico-legal issues. Despite the long list of other blood...