CLINICAL CHARACTERISTICS AND RADIOLOGICAL MANIFESTATIONS IN INFLUENZA A AND (H1N1) SWINE FLU INFECTION: OUR EXPERIENCE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 25
Abstract
BACKGROUND The study was carried out during July 2017 through October 2017 when there was a seasonal epidemic of influenza like illness (ILI) in Odisha. MATERIALS AND METHODS We collected data of 36 cases confirmed out of 152 suspected cases by reverse - transcriptase - polymerase chain assay of sampling of nasopharyngeal swab or pharyngeal secretions at Regional Medical Research Centre (ICMR), Bhubaneswar from clinical presentations of influenza illness. RESULTS Results of the 36 confirmed patients studied, 9 were influenza A positive H1N1neg and 27 influenza A & H1N1 (swine flu) positive. 22.2% of cases were below 19 yrs., whereas those above 60yrs in both groups were 33.3% and 25.9% respectively. In the H1N1 positive cases, diabetes mellitus and cardiovascular disease each constituted 18.5% amongst the comorbidities. All cases underwent chest radiography on admission. Bronchovascular prominence and bilateral consolidation were most frequently observed (37.1 & 33.3% respectively). HRCT performed in cases having normal chest X-ray revealed tree in bud and nodular pattern. Out of the total confirmed cases, 4 died (11.1%). Qualitative risk factors like renal failure, sepsis and ARDS were associated with mortality (p value< 0.05). Quantitative risk factors like low mean arterial pressure and raised serum creatinine were associated with mortality (p<0.001). Use of antiviral drug Oseltamivir initiated at a mean of 5.83 days was beneficial among the survivors. CONCLUSION During the seasonal epidemics, influenza-A both H1N1 negative and positive cases caused illness requiring hospitalisation. Severe illness with renal failure, sepsis, hypotension, ARDS had mortality outcome. Patients seem to benefit from early antiviral therapy.
Authors and Affiliations
Chinnari Mohan Rao, Saswat Subhankar, Debee Prasad Dash
Keywords
Related Articles
- EP ID EP567062
- DOI 10.18410/jebmh/2018/400
- Views 94
- Downloads 0
CERVICAL INTRAEPITHELIAL LESIONS IN HIV AND NON-HIV WOMEN ATTENDING ART CENTRE AND GYNAEC OPD IN RAICHUR INSTITUTE OF MEDICAL SCIENCES, RAICHUR
Cancer cervix is the second most common cancer in women. Infection with HPV has been implicated in pre-cancerous squamous intraepithelial lesions and their progression to cervical cancer. The risk of infection with HPV i...
A RARE CASE OF FATAL ARACHNOID CYST OF CEREBELLO-PONTINE ANGLE
A 29-year-old apparently healthy adult male collapsed following a heavy meal and was taken to a teaching hospital in half an hour and was declared dead on arrival. There was no history of hypertension or diabetes mellitu...
STUDY OF SUPRACONDYLAR FRACTURE OF HUMERUS IN CHILDREN BY OPEN REDUCTION AND INTERNAL FIXATION WITH K-WIRES
BACKGROUND Supracondylar fractures of humerus is one of the commonest injury. It constitutes about 65 of all fractures around the elbow in children. Displaced supracondylar fracture of humerus requires accurate anatomica...
ESTIMATION OF pH, TOTAL ACID AND ETHANOL CONTENT OF COMMERCIALLY AVAILABLE ALCOHOL-CONTAINING MOUTHWASHES AND ITS EFFECT ON SALIVARY pH
BACKGROUND Use of mouthwash has become widespread as a part of routine oral hygiene. Mouthwashes may have deleterious effects on oral tissues because of its low pH, high acid content and use of ethanol as an antiseptic a...
CAMP-BASED SCREENING OF PRIMARY OPEN ANGLE GLAUCOMA IN A RURAL VILLAGE OF SOUTH ORISSA
BACKGROUND Glaucoma is the second most common cause of blindness worldwide and is responsible for 10% of blindness worldwide. Primary open angle glaucoma being more common than primary angle closure glaucoma. MATERIALS A...