CLINICAL CHARACTERISTICS AND RADIOLOGICAL MANIFESTATIONS IN INFLUENZA A AND (H1N1) SWINE FLU INFECTION: OUR EXPERIENCE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 25
Abstract
BACKGROUND The study was carried out during July 2017 through October 2017 when there was a seasonal epidemic of influenza like illness (ILI) in Odisha. MATERIALS AND METHODS We collected data of 36 cases confirmed out of 152 suspected cases by reverse - transcriptase - polymerase chain assay of sampling of nasopharyngeal swab or pharyngeal secretions at Regional Medical Research Centre (ICMR), Bhubaneswar from clinical presentations of influenza illness. RESULTS Results of the 36 confirmed patients studied, 9 were influenza A positive H1N1neg and 27 influenza A & H1N1 (swine flu) positive. 22.2% of cases were below 19 yrs., whereas those above 60yrs in both groups were 33.3% and 25.9% respectively. In the H1N1 positive cases, diabetes mellitus and cardiovascular disease each constituted 18.5% amongst the comorbidities. All cases underwent chest radiography on admission. Bronchovascular prominence and bilateral consolidation were most frequently observed (37.1 & 33.3% respectively). HRCT performed in cases having normal chest X-ray revealed tree in bud and nodular pattern. Out of the total confirmed cases, 4 died (11.1%). Qualitative risk factors like renal failure, sepsis and ARDS were associated with mortality (p value< 0.05). Quantitative risk factors like low mean arterial pressure and raised serum creatinine were associated with mortality (p<0.001). Use of antiviral drug Oseltamivir initiated at a mean of 5.83 days was beneficial among the survivors. CONCLUSION During the seasonal epidemics, influenza-A both H1N1 negative and positive cases caused illness requiring hospitalisation. Severe illness with renal failure, sepsis, hypotension, ARDS had mortality outcome. Patients seem to benefit from early antiviral therapy.
Authors and Affiliations
Chinnari Mohan Rao, Saswat Subhankar, Debee Prasad Dash
Keywords
Related Articles
- EP ID EP567062
- DOI 10.18410/jebmh/2018/400
- Views 74
- Downloads 0
MATERNAL FACTORS AFFECTING NEWBORN WEIGHT AT TERM- A STUDY IN A REFERRAL HOSPITAL
BACKGROUND Maternal factors known to contribute to low birth weight (LBW) include biological factors, nutritional factors, low socio-economic class, poor education, medical and obstetric problems. The aim and objective o...
LEFT RENAL TUMOR: A RARE CADAVERIC FINDINGS
A benign tumour is a non-cancerous growth that does not spread (metastasize) to other parts of the body and is not usually life-threatening. Many researchers believe that most of the following types of kidney tumours are...
A COMPARATIVE STUDY OF PEDIATRIC CARDIAC CATHETERIZATION PROCEDURE UNDER GENERAL ANESTHESIA WITH OR WITHOUT FEMORAL NERVE BLOCK
OBJECTIVE Anesthetic management for interventional cardiac procedures/cardiac catheterization in pediatric patients is challenging. Cardiac anomalies vary from simple to complex congenital cardiac anomalies, shunts may b...
TRENDS IN SEROPREVALENCE OF TRANSFUSION TRANSMISSIBLE INFECTIONS AMONGST THE BLOOD DONORS IN TERTIARY CARE CENTRE
BACKGROUND Blood transfusion carries the potential risk of transfusion transmissible infections (TTIs) making it the most dreaded complication of blood transfusion. The objective was to study the trends in seroprevalence...
INTERPRETATION OF FNA SMEARS
Fine needle aspiration cytology (FNAC) is a well-established investigation step in the evaluation of patients in current clinical practice. However there is little awareness about the best practices in this field of cyto...