Clinical Evaluation of Sequential Application of Pulsed Dye Laser with 1064 Neodymium: Yttrium-Aluminum-Garnet Laser in the Treatment of Psoriasis
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 9
Abstract
Background: Angiogenesis has a crucial role in the pathogenesis and the maintenance of psoriasis. Dilated tortuous blood vessels can be acted upon by vascular lasers according to the principle of Anderson and Parrish. Objective: The goal of this study was to evaluate the efficacy of the sequential application of pulsed dye laser (PDL) with Nd: YAG laser in the treatment of plaque psoriasis. Design: This was a prospective clinical trial with a three-month follow-up. Patients and Methods: Thirty three patients with chronic and stable plaque type psoriasis were included in this study. Patients received 7 sequential PDL + Nd: YAG laser treatments at two weeks intervals. Intervention: Intervention included the application of seven sequential PDL and Nd: YAG laser treatments at two weeks intervals. Outcome Assessment: Evaluation of clinical improvement by examination and photography. Results: All patients showed a significant decrease in modified Psoriasis Area and Severity Index (m PASI) score. Conclusion: Combined PDL + Nd: YAG presents a new therapeutic option for the treatment of plaque psoriasis.
Authors and Affiliations
Dr. Noha G. Abdallah
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