Community-Acquire CTX-M Beta-Lactamase Enteric Isolates in Abeokuta, Nigeria
Journal Title: Microbiology Research Journal International - Year 2015, Vol 5, Issue 4
Abstract
Aim: To study the emergence of the community-acquire CTX-M beta-lactamase genes among the residents in Abeokuta, Nigeria. Study Design: To determine the prevalence rate of CTX-M beta-lactamase genes in enteric multi-resistant ESBL isolates found among the Abeokuta residents. Place of Study: Abeokuta, Nigeria between August 2010 and March 2013. Methodology: Beta-lactamase and ESBL producing enteric bacteria were identified and their antimicrobial susceptibility was tested against commonly used antibiotics. Mating activity of the isolates was evaluated and their plasmid was profiled while a CTX-M chromosomal gene was assayed by PCR. Results: Of the 27.4% beta-lactamase producers obtained, only 5.1% of the strains were ESBL and 2.8% harboured blaCTX-M genes. High resistance rate of 91.0% by Escherichia coli and Klebsiella oxytoca to commonly used antibiotics was observed. Conclusion: There is urgent need to curb the community spread of undetected mobile genetic elements of CTX-M-encoded enteric bacteria among the residents in this community and if this persists, a possible outbreak of enteric infection caused by resistant organisms is eminent.
Authors and Affiliations
P. A. Akinduti, A. Oluwadun, B. Iwalokun, O. M. Onagbesan, O. Ejilude
Keywords
Related Articles
- EP ID EP354430
- DOI 10.9734/BMRJ/2015/5622
- Views 84
- Downloads 0
Molecular and Serological Studies for Detection and Identification of Cotton Leaf Curl Virus in Cotton Plant (G. barbadense L.) in Egypt
Aims: Cotton production contributes in economic security in Egypt. Cotton leaf curl virus (CLCuV) belongs to the Begomovirus genus and Geminiviridae family that is transmitted by the whitefly Bemisia tabaci. It is the g...
DNA Microarray-based Identification of Fungal Pathogens in Neutropenic Patients in Alexandria University Hospitals in a Twelve-month Interval
Background: Systemic fungal infections are increasing, and they cause severe morbidity and high mortality rates among immuno-compromised patients. Conventional laboratory methods for identifying fungal pathogens, althoug...
Isolation and Identification of Potential Probiotics Bacteria from the Gut of Oreochromis niloticus and Clarias gariepinus in Uganda
Bacterial infections remain a hindrance to aquaculture expansion globally. Increased fish mortality and poor performance resulting from ill health has forced farmers to resort to the use of antibiotics globally. However,...
Optimization of β-galactosidase Production from Yogurt and Dairy Soil Associated Bacteria Using Different Fermentation Media
Aims: The aim of current research was the production of β-galactosidase enzyme from Lactobacillus delbruekii subsp. bulgaricus isolated form yogurt and soil samples. Study Design: Production of β-galactosidase. Place a...
Evaluation of Different Screening Methods for Biosurfactant Producers Isolated from Contaminated Egyptian Samples Grown on Industrial Olive Oil Processing Waste
The present study aimed to screen biosurfactant producing microorganisms isolated from different Egyptian samples viz. soil sample contaminated with oil from fuel station, soil sample contaminated with kerosene from clas...