Comparative Evaluation of Platelet-Rich Fibrin Biomaterial and Open Flap Debridement in the Treatment of Intrabony Defects
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 12
Abstract
Background: Platelet-rich concentrates are the most widely used regenerative biomaterials. Stimulation and acceleration of soft and hard tissue healing are due to local and continuous delivery of growth factors and proteins, mimicking the needs of the physiological wound healing and reparative tissue processes. This article aims to evaluate the clinical efficacy of open flap debridement (OFD) with or without platelet-rich fibrin (PRF) in the treatment of intrabony defects. Methods: Fifteen subjects with thirty intrabony defects were treated with either autologous PRF with open-flap debridement (test, n = 15) or open-flap debridement alone (control, n = 15). Parameters included: relative attachment level and alveolar crest to the base of the defect (AC-BOD). The parameters were recorded at baseline and at 12 months postoperatively. Results: Statistically significant (0.005) improvements were seen with all the parameters in test group than control groups. Conclusion: Adjunctive use of PRF with OFD significantly improves defect fill when compared to OFD alone. PRF has consistently been showing regenerative potential; it is simple, easy and inexpensive biomaterial compared with bone grafts.
Authors and Affiliations
Dr Gazanfer Ali Shah, Dr Suhail Majid Jan, Dr Reyaz Ahmad Mir Tutor, Dr Beanish
Keywords
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- EP ID EP428650
- DOI 10.9790/0853-1712114752.
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