Comparative Seed Morphology, Pharmacognostic, Phytochemical, and Antioxidant Potential of Memecylon L. Fruits
Journal Title: Turkish Journal of Pharmaceutical Sciences - Year 2021, Vol 18, Issue 2
Abstract
Objectives: Memecylon is the genus of the family Melastomataceae and their identification is somewhat difficult as a result of similarities in their intraspecies morphologies. Thus, identification of these species is much strenuous. The present study investigated the seed morphology, pharmacognostic, phytochemical, and antioxidant potential of Memecylon fruits. Materials and Methods: The species Memecylon grande, Memecylon randerianum and Memecylon umbellatum were selected for this study. The surface morphology of seeds or fruits, pharmacognostic evaluation, and phytochemical analysis are effective methods for rectifying taxonomic difficulties in authentication process and it opens a platform for pharmaceutical analysis. The surface morphology was analyzed by scanning electron microscopy (SEM) and elemental compositions were revealed by using energy dispersive X-ray spectroscopy (EDX) and inductively coupled plasma-mass spectroscopy (ICP-MS). While evaluating the pharmacognostic property of the seeds, powder microscopic analysis was used, which focusesd on the functional purity of the fruit samples. 2,2-diphenyl-1-picrylhydrazyl, hydroxyl, nitric oxide and superoxide radical scavenging assays are carried out to determine the antioxidant potential of Memecylon fruits. Results: The surface morphology of seeds had a distinct pattern of topography. SEM and EDX studies gave an insight on the elemental composition of the seeds. ICP-MS analysis showed the presence of biologically potent trace elements in the fruit samples. Quantitative estimation of secondary metabolites, such as alkaloids, terpenoids, flavonoids, and phenols, revealed that fruit extracts possess a significant amount of these phytoconstituents. The present study also reveals the antioxidant potential of Memecylon fruit extracts. Conclusion: Powder microscopy, SEM, EDX and ICP-MS analyses provided knowledge about the functional purity and elemental composition of Memecylon fruits samples. The free radical scavenging assays showed that Memecylon fruits were natural antioxidant sources. Therefore, these findings can be effectively targeted toward the pharmacological utilization of Memecylon fruits.
Authors and Affiliations
P. R. RAMYA SREE, J. E. THOPPIL
Keywords
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- DOI 10.4274/tjps.galenos.2020.82956
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