COMPARISON OF LABETOLOL AND ESMOLOL IN ATTENUATING THE SYMPATHETIC RESPONSE TO LARYNGOSCOPY AND INTUBATION
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 11
Abstract
BACKGROUND: To Compare the attenuation of the sympathomimetic response to laryngoscopy and Intubation of the two drugs Labetolol (0.25mg/kg) and Esmolol (0.5mg/kg) in low doses. METHODS: In a prospective randomized study, 75 patients were selected for different types of elective surgeries under general anesthesia and divided into 3 groups of 25 each. Group C, Group E and Group L They were given 10ml of 0. 9% normal saline, 0.25mg of labetolol and 0.5mg of Esmolol respectively. We compared the degree of attenuation of the sympathomimetic response to laryngoscopy and intubation in these three groups. RESULTS: The Group L patients who received low doses of 0.25mg/kg of labetolol showed greater attenuation to the sympathomimetic response to laryngoscopy and Intubation in terms of heart rate and systolic blood pressure than the Group E who recieved esmolol 0.5mg /kg. But there was no change in both the groups regarding the Diastolic blood pressure and Mean arterial pressure in response to laryngoscopy and Intubation. CONCLUSION: We concluded that Labetolol in low doses of 0. 25mg/kg showed better attenuation of sympathomimetic response to laryngoscopy and intubation compared to Esmolol of 0.5mg/kg.
Authors and Affiliations
Gilakala Varaha Ganesh, Saroj Patta, Bhaskara P. N. V.
Keywords
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- EP ID EP226433
- DOI 10.18410/jebmh/2015/232
- Views 78
- Downloads 0
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