Concentric bioprinting of alginate-based tubular constructs using multi-nozzle extrusion-based technique
Journal Title: International Journal of Bioprinting - Year 2015, Vol 1, Issue 1
Abstract
Bioprinting is a layer-by-layer additive fabrication technique for making three-dimensional (3D) tissue and organ constructs using biological products. The capability to fabricate 3D tubular structure in free-form or vertical configuration is the first step towards the possibility of organ printing in three dimensions. In this study, alginate-based tubular structures of varying viscosity were printed vertically using multi-nozzle extrusion-based technique. Manufacturing challenges associated with the vertical printing configurations are also discussed here. We have also proposed measurable parameters to quantify the quality of printing for systematic investigation in bioprinting. This study lays a foundation for the successful fabrication of viable 3D tubular constructs.
Authors and Affiliations
Edgar Y. S. Tan, Wai Yee Yeong
Keywords
Related Articles
- EP ID EP678633
- DOI -
- Views 200
- Downloads 0
3D bioprinting for tissue engineering: Stem cells in hydrogels
Surgical limitations require alternative methods of repairing and replacing diseased and damaged tissue. Regenerative medicine is a growing area of research with engineered tissues already being used successfully in pati...
Formation of cell spheroids using Standing Surface Acoustic Wave (SSAW)
3D bioprinting becomes one of the popular approaches in the tissue engineering. In this emerging application, bioink is crucial for fabrication and functionality of constructed tissue. The use of cell spheroids as bioink...
Solvent-based Extrusion 3D Printing for the Fabrication of Tissue Engineering Scaffolds
Three-dimensional (3D) printing has been emerging as a new technology for scaffold fabrication to overcome the problems associated with the undesirable microstructure associated with the use of traditional methods. Solve...
A novel bioactive PEEK/HA composite with controlled 3D interconnected HA network
Polyetheretherketone (PEEK) is a high-performance thermoplastic biomaterial which is currently used in a variety of biomedical orthopaedic applications. It has comparable tensile and compressive strength to cortical bone...
Microstereolithography-fabricated microneedles for fluid sampling of histamine-contaminated tuna
A custom-designed microneedle sampling system was prepared using dynamic mask microstereolithography; this sampling system was used for determination of histamine content in fresh, histamine-spiked, and spoiled tuna fles...