Concentric bioprinting of alginate-based tubular constructs using multi-nozzle extrusion-based technique
Journal Title: International Journal of Bioprinting - Year 2015, Vol 1, Issue 1
Abstract
Bioprinting is a layer-by-layer additive fabrication technique for making three-dimensional (3D) tissue and organ constructs using biological products. The capability to fabricate 3D tubular structure in free-form or vertical configuration is the first step towards the possibility of organ printing in three dimensions. In this study, alginate-based tubular structures of varying viscosity were printed vertically using multi-nozzle extrusion-based technique. Manufacturing challenges associated with the vertical printing configurations are also discussed here. We have also proposed measurable parameters to quantify the quality of printing for systematic investigation in bioprinting. This study lays a foundation for the successful fabrication of viable 3D tubular constructs.
Authors and Affiliations
Edgar Y. S. Tan, Wai Yee Yeong
Keywords
Related Articles
- EP ID EP678633
- DOI -
- Views 167
- Downloads 0
Post-printing surface modification and functionalization of 3D-printed biomedical device
3D printing is a technology well-suited for biomedical applications due to its ability to create highly complex and arbitrary structures from personalized designs with a fast turnaround. However, due to a limited selecti...
Electrospun 3D multi-scale fibrous scaffold for enhanced human dermal fibroblasts infiltration
Electrospun polymeric nanofibrous scaffold possesses significant potential in the field of tissue engineering due to its extracellular matrix mimicking topographical features that modulate a variety of key cellular activ...
Solvent-based Extrusion 3D Printing for the Fabrication of Tissue Engineering Scaffolds
Three-dimensional (3D) printing has been emerging as a new technology for scaffold fabrication to overcome the problems associated with the undesirable microstructure associated with the use of traditional methods. Solve...
Graphene Oxide Induces Ester Bonds Hydrolysis of Poly-l-lactic Acid Scaffold to Accelerate Degradation
Poly-l-lactic acid (PLLA) possesses good biocompatibility and bioabsorbability as scaffold material, while slow degradation rate limits its application in bone tissue engineering. In this study, graphene oxide (GO) was i...
Bioprinting of Multimaterials with Computer-aided Design/Computer-aided Manufacturing
Multimaterials deposition, a distinct advantage in bioprinting, overcomes material’s limitation in hydrogel-based bioprinting. Multimaterials are deposited in a build/support configuration to improve the structural integ...