CONTEMPORARY ASPECTS OF THE PATHOGENESIS OF SYSTEMIC NECROTIZING VASCULITIS
Journal Title: Ukrainian Scientific Medical Youth Journal / Український Науково-Медичний Молодіжний Журнал - Year 2013, Vol 71, Issue 1
Abstract
This article presents the recent published data about the pathogenesis of systemic necrotizing vasculitis. It is demonstrated a pathogenetic role of anti- neutrophil cytoplasmic antibodies, antibodies to lysosome- associated membrane protein 2, endothelial dysfunction and its markers, T- and B-lymphocytes in the development of this disease. These features of the pathogenesis have to beat the basis for development of the new effective treatment options for patients with systemic necrotizing vasculitis.
Authors and Affiliations
L. Petelytska, O. laremenko, H. lurieva
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