Coronavirus disease 2019 (COVID-19): A New Pandemic and its Challenges
Journal Title: Journal of Current Biomedical Reports - Year 2020, Vol 1, Issue 2
Abstract
Emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide outbreak and a major public health problem. The present review was conducted to provide brief information about the origin, symptoms, transmission, pathogenesis, diagnosis, and treatment of the virus. A search was performed in the databases of PubMed, Scopus, Science Direct, and Google scholar with English keywords including 2019-nCoV, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, and novel coronavirus from December 2019 to 15 March 2020, and the search results were evaluated. Selected studies have shown that the virus may have originated from the bat. It has also been shown that the virus receptor is angiotensin-converting enzyme 2 (ACE2) which is also the SARS virus receptor and is expressed in most human tissues. The most common way of virus transmission was suggested through respiratory droplets and close contact. It is also transmitted by asymptomatic patients, but vertical transmission from mother to fetus has not been confirmed. Real-time reverse transcriptase (RT)-PCR is the gold standard for SARS-CoV-2 detection, but chest computed tomography (CT) can be more sensitive to detect positive cases. Since no effective vaccine or drug for prevention and treatment of this disease has not yet been identified and also because of the high incubation and infection period, easy transmission, and the lack of complete recognition of the characteristics and stability in different environments, the best way to control of COVID-19 is to prevent the spread of the infection in different ways and take seriously personal and public hygiene.
Authors and Affiliations
Davood Mansury, Sharareh Moghim
Keywords
Related Articles
- EP ID EP690385
- DOI -
- Views 304
- Downloads 0
Coronavirus disease 2019 (COVID-19): A New Pandemic and its Challenges
Emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide outbreak and a major public health problem. The present review was conducted to provide brief information about the origin,...
Molecular characterization of Panton-Valentine Leukocidin positive Staphylococcus aureus isolates obtained from clinical sample in Isfahan, Iran
Staphylococcus aureus is one of the main significant human pathogens which can produce various toxins such as Panton-Valentine Leukocidin (PVL) which is known as a prominent toxin associated with S. aureus infections. PV...
Decrease of microbial contamination by application of routinely glycerol and phenol solution on human cadavers
Human cadaver is imperative learning material for medical students. The cadavers expose to microbial contamination every time anatomists work with them. The microorganisms found in preparations’ cadavers could be pathoge...
Investigating the effect of ghrelin on improving memory and learning ability in animals: A systematic review
Ghrelin does an important role in neurological functions such as memory, learning, and cognition as well. There is some evidence that ghrelin can improve memory. This study aimed to evaluate the effects of ghrelin on rat...
Evaluation of clinical and laboratory causes of burns in pre-school children
We investigate characteristics of burns in children aged up to seven years and hospitalized at Velayat burn center unit for two years to evaluate clinical and laboratory causes of burns in pre-school children. In a retro...