Current status of metrological traceability and measurement uncertainty in clinical laboratories
Journal Title: Journal of Analytical Bio-Science - Year 2011, Vol 34, Issue 3
Abstract
Standardization is the most important issue in laboratory medicine. ISO has established the metrological traceability in laboratory medicine as International Standard 17511. Many countries have studied standardization programs based on ISO 17511. Traceability chains have been constituted for measuring biochemical components in clinical chemistry. It is necessary to apply such uncertainty to routine laboratory results. Uncertainty is secured the hierarchy in traceability chain. A thorough evaluation of uncertainty in routine measurement procedures is needed. It is considered that patients' results will estimate the reliability using uncertainty test results.
Authors and Affiliations
Yoshiaki Iizuka, Katsuhiko Kuwa
Keywords
Related Articles
- EP ID EP113657
- DOI -
- Views 101
- Downloads 0
New creatine kinase assay kit for clinical analyzers- Know-How and techniques for reagent stabilization -
Creatine kinase (CK) is an essential enzyme that is present in various tissues like skeletal muscle, myocardium or brain, and it plays a crucial role in energy metabolism. During muscle or myocardial injury, CK is releas...
Disease diagnosis with electrophoretic analysis of urinary protein and comprehensive urinary proteome research
The importance of urine has tended to be underestimated given its image of an unnecessary waste of biological fluid. Recently, large-scale projects have been established to analyze urinary proteins, more than 1500 of whi...
Octacosanol ameliorates hyperlipidemia and oxidative stress in KKAy mice with type 2 diabetes
We examined the effect of octacosanol (Oct) on hyperlipidemina and oxidative stress in type 2 diabetic KKAy mice. KKAy mice showed increases in body weight and serum glucose, insulin, triglyceride, total-cholesterol, and...
High sensitive determination of oxysterols in human plasma using gas chromatography-mass spectrometry (GC-MS)
Oxysterols, cholesterol oxidation products, have been important markers for various diseases. For example, it is suggested that 24S-hydroxycholesterol, 27-hydroxycholesterol and 7-ketocholesterol can be used as a marker...
Lifestyle-related diseases in Okinawa school children -Dyslipidemia, Obesity and metabolic syndrome-
Cardiovascular disease (CVD) risk factors are associated with weight status and/or insulin resistance. However, these associations are not fully understood in schoolchildren. In the present study, we investigated the rel...