Cytological evaluation of lymph node aspirates, correlation with clinical findings and histopathology at a tertiary care center in the Konkan belt of Maharashtra state, India
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 8, Issue 2
Abstract
Background: The present Konkan region based study has been taken up to study the FNAC in the lesions of lymph nodes and to study the different cyto-morphological patterns associated with various lymphadenopathies from different sites in well stained smears. The cytodiagnosis was compared with available histopathology, thus verifying the accuracy of FNAC. Methods: The present study is a retrospective study carried out from 1/8/2016 to 31/7/2018. The Fine needle cytology material consisted of 70 patients with Lymph node swellings from different sites coming to Pathology department with various complaints. The study period was of three years’ duration. The alcohol fixed (PAP, HandE) and air dried smears (MGG, AFB) smears of nodal lesions were studied for cytomorphological features. Histopathology correlation was done, wherever possible. Results: Overall incidence of lymph node FNACS was 2.16 %. 51 were males (72%) and 19 were females (27 %). Majority of the lymph node FNAC cases were in 6th decade of life. Most common site of lymphadenopathy was cervical nodes (64.28%) followed by submandibular lymph nodes (17.14%). Most common cytological diagnosis of lymph-node FNAC was metastatic squamous cell carcinoma (44.28%) followed by inadequate opinion cases (Inadequacy rate-18.57 %). Inflammatory conditions (lymphadenitis) in lymph node FNACs were 14.29%. Lymphoid malignancies were seen in 68.57%. Lymphoma cases in toto were diagnosed in 12.86%. Metastasis was diagnosed in 54.29%. Histopathology (gold standard test) correlation with cytological findings of nodal FNACs were available in 43/70 cases. Maximum cases were nodal metastasis of squamous cell carcinoma on cyto-histo correlation. Conclusion: Cervical lymph nodes were main sites for nodal metastasis from oral-cavity tumors as oral cancers are more prevalent in our Konkan belt. Correlation of lymph node smear cytology with ‘gold standard’ histological reports revealed excellent diagnostic parameters, implying the efficacy of cost-effective, cheaper, simple procedure of smear cytology.
Authors and Affiliations
Bhushan Malhari Warpe, Shweta Joshi-Warpe, Divyanka Sahadev Sawant
Keywords
Related Articles
- EP ID EP457192
- DOI 10.26611/105824
- Views 78
- Downloads 0
Study of lipid profile in patients with myocardial infarction
Background: Myocardial infarction is one of the leading cause of death worldwide Dyslipidemia is been considered to be a risk factor for development of myocardial infarction, Present study is intended to know association...
Cytopathological study of thyroid lesions by fine-needle aspiration cytology at tertiary care center in Saurashtra region
Background: Fine needle aspiration cytology (FNAC) is the easiest, simple and rapid diagnostic procedure amongst all the diagnostic tests for evaluation of thyroid lesions. It is important to diagnose benign and malignan...
Clinico-cytological and radiological correlation of sputum analysis in a tertiary care hospital
Background: Sputum, a specialized product of the respiratory tract, is formed as a result of interaction between mucociliary apparatus, immune system of the host and animate, inanimate invaders from the environment. It i...
Evaluation of microRNA 196a expression in cervical carcinoma
Cervical carcinoma is the second most common cancer next to breast carcinoma in women and most leading cause of death in women in developing nations which compels the need of investigating the molecular mechanisms that a...
Knowledge, attitude and practices regarding voluntary blood donation
Background: The availability of safe and good quality blood is crucial in improving medical facilities in a society. A study on the KAP of the donors may prove to be useful in the successful implementation of the blood d...