DECLININE: THE NEW ALKALOID FROM PHOEBE DECLINATA NEES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2014, Vol 5, Issue 4
Abstract
The new alkaloid named as declinine had been isolated from stem bark of Phoebe declinata Nees (Lauraceae). This alkaloid had been obtained for the first time from this plant. The structure of declinine was determined by spectroscopic analysis of 1D and 2D NMR, IR, UV, and LCMS. Declinine exhibited good antioxidant activity by DPPH assay with an IC50 value 11.8 µg/mL compared to boldine as a standard with an IC50 value 5.8 µg/mL.
Authors and Affiliations
Elya Berna , Roshamur Forestrania, Harmita , Hanita Omar, Katrin , Rosmalena , Zakiyah Ulfah
Keywords
Related Articles
- EP ID EP157565
- DOI 10.7897/2230-8407.050458
- Views 98
- Downloads 0
EVALUATION OF ANTIOXIDANT ACTIVITY IN ETHANOLIC EXTRACTS OF FIVE CURCUMA SPECIES
The Zingiberaceae, the largest family in the Zingiberales, comprises nearly 50 genera and 1,000 species and is pantropical, concentrated mainly in the old world, chiefly in Indo-malaysia. Members of the family yield spic...
ANTITUMOR ACTIVITY OF METHANOLIC EXTRACT OF TERMINALIA CATAPPA LEAVES AGAINST EHRLICH ASCITES INDUCED CARCINOMA IN MICE
Terminalia catappa belongs to the family combretaceae and is popularly known as badam.It is a well known herb in Ayurvedic system of medicine The aim of the present study is to evaluate the effect of methanolic extract...
IN VITRO EVALUATION OF ANTIOXIDANT ACTIVITY OF SPONDIAS MOMBIN LEAF EXTRACT: DISCOVERING FUTURE AVENUES FOR AN AFFORDABLE AND EFFICIENT ANTIOXIDANT
Spondias mombin is valued ethno medically in folkloric medicine. This medicinal plant according to traditional claim is said to cure various infectious and inflammatory ailments of gastrointestinal and genitourinary trac...
QUANTITATIVE PHYTOCHEMICAL AND GC-MS ANALYSIS OF LEAF AND BARK EXTRACT OF DOLICHANDRONE ATROVIRENS
The present study deals with the quantitative phytochemical and GC-MS analysis of aqueous methanolic bark and leaf extract of Dolichandrone atrovirens. This study concerns the quantitative screening of total glycosides,...
POLYLACTIDE-CO-GLYCOLIDE NANOPARTICLES THERAPEUTIC BENEFITS IN CANCER
Anticancer therapy majorly hindered by drug low water solubility, poor drug permeability, and high efflux of drug from cells. Nanotechnology is severing as an important tool to overcome these problems of cancer drug ther...