DESIGN DEVELOPMENT AND EVALUATION OF MODIFIED RELEASE TABLET OF MONTELUKAST SODIUM USING ETHYL CELLULOSE AND TRAGACANTH
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 1
Abstract
The purpose of this research was to prepare a modified release tablet of montelukast sodium. Montelukast sodium is Leukotriene antagonist which is rapidly absorbed after the oral administration. The drug was mixed with Ethyl Cellulose and Tragacanth as a dry binder and ethanol was used as solvent to perform the granulation in FBD by the bottom spray method. The granules obtain were mixed with the other ingredients and were compressed using 10 station tablet rotary press. The dissolution was carried out using USP paddle apparatus.
Authors and Affiliations
Krunal M Patel
Keywords
Related Articles
- EP ID EP134956
- DOI -
- Views 102
- Downloads 0
FORMULATION AND EVALUATION OF FILM COATED TICLOPIDINE HYDROCHLORIDE IMMEDIATE RELEASE TABLETS
In the present work attempts were made to with an aim to develop pharmaceutically equivalent, stable, cost effective and quality improved formulation of film coated Ticlopidine Hydrochloride immediate release tablets by...
MONITORING OF OSTEOPOROSIS TREATMENT
Osteoporosis is far the most common metabolic bone disease and is often called the "silent" disease, because bone loss occurs without symptoms. People often don't know they have the disease until bone breaks, following t...
PELLETIZATION TECHNIQUES: A LITERATURE REVIEW
In present times, the pelletization technologies are gaining much attention as they represent an efficient pathway for manufacture of oral drug delivery systems. This is due to the reason that pellets offer many therapeu...
ETHNOMEDICINAL KNOWLEDGE AMONG THE ADI TRIBES OF LOWER DIBANG VALLEY DISTRICT OF ARUNACHAL PRADESH, INDIA
The paper presents the traditional ethnomedicinal knowledge and uses of various plants among the Adi tribes of Lower Dibang Valley district of Arunachal Pradesh (India). These people in rural villages are still more or l...
EVALUATION OF IN VITRO STABILITY STUDIES ON NUTRACEUTICALS IN ORAL SOLID DOSAGE FORMS WITH SPECIAL REFERENCE TO GLUCOSAMINE
Pure Glucosamine is very "hygroscopic" and degrades (breaks down) rapidly when exposed to moisture or air. To avoid this, Glucosamine needs to be bound to a stabilizer to be sold commercially. The sulfate and the HCL for...