Determination of Polyphenols and Anti-Inflammatory Activity of Aqueous and Ethanolic Extracts of Erythroxylum Emarginatum (Erythroxylaceae)
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
Our work was part of the search for new active molecules in the inflammatory process to relieve pain more effectively. Erythroxylum emarginatum is a plant distributed in tropical regions of South America, Africa, and Madagascar. The phytochemical screening has shown that the bark of stems contained more full of polyphenols than the leaves. Erythroxylum emarginatum is known for its anti-inflammatory properties, its use in the treatment of bronchial affections and especially during asthma. The comparative study of Erythroxylum emarginatum bark of stems aqueous and ethanolic extracts with diclofenac on induced inflammation of rat paw by carrageenan revealed anti-inflammatory properties of both extracts. In effect at doses of 200 mg/kg of body weight, both extracts have anti-inflammatory properties comparable to those of diclofenac dosed at 25mg/kg body weight. These results would justify the use of Erythroxylum emarginatum bark of stems by people to prevent inflammatory processes in arthritis and asthma.
Authors and Affiliations
Kouakou Kouakou Victor1, Opkekon Aboua Timothee. ², Kouakou - Siransy Gisele, Yapi Houphouet Felix¹, Gbassi Komenan Gildas4
Keywords
Related Articles
- EP ID EP385905
- DOI -
- Views 66
- Downloads 0
Follicular fluid cell free DNA in poly cystic ovary syndrome patients undergoing intracytoplasmic sperm injection program: relation to ovarian reserve and embryo quality
Poly cystic ovary syndrome [PCOS] represents the most common disorder in women during reproductive age. Because of the expensiveness and invasiveness of in vitro fertilization procedures [IVF], it has been tried to find...
Bacterial Alkaline Laccase and Its Environmental Applications
Alkaline laccase play an important role in bioremediation such as degradation of phenols, aromatic hydrocarbons, and different dyes used in textile industry. Also in denim washing, cosmetics and pulping industry. The iso...
Effect of Additive Tamoxifen Citrate to SMART Medium on Human Sperm Parameters during In vitro Sperm Activation
This study was aimed to investigate the effect of addition of tamoxifen citrate on the outcome of in vitro human sperm activation. One hundred semen samples for fertile and infertile men were randomly collected from the...
Removal of the Bad Effects of D-Galactosamine on Blood Lipids of Male Wistar Rats By Black and Green Tea Consumption
There is an increase in overall health awareness in Saudi Arabia due to a rising rate of diseases such as diabetes and heart diseases in addition to obesity. Thus, Saudi Ministry of Health initiates many programs to impr...
Fungal Profile of Occular Infection in Patients Attending In a Tertiary Care Hospital
Aim and objective: To identify the fungal etiology of Ocular infections in patients attending Ophthalmology department from the period Nov 2010 to Sep 2011 at Navodaya Medical College Hospital and Research Centre, Raichu...