Differential influence of age on Autonomic Reactivity – A Comparative Study
Journal Title: Applied Physiology and Anatomy Digest - Year 2018, Vol 3, Issue 2
Abstract
Background: Normal human ageing is associated with changes in the autonomic control of several biological functions. The sympathetic and parasympathetic nervous systems mature with time, but degree of the changes due to ageing are different. Aim: The present study compares the effect of ageing on autonomic function parameters among subjects of three age groups above 40 years of age. Methodology: In present study 100 Normal healthy subjects were divided into 3 groups as, Group I (41-50yrs), Group II (51-60yrs) and Group III (61-70yrs). Autonomic function tests were Heart rate and BP response to sustained handgrip, cold pressor test, Valsalva ratio and deep breathing difference. One way ANOVA tests and Pearson’s correlation were used for statistical analysis. Results: SBP response to sustained handgrip was significantly lower in group III (9.42 ± 4.81) than group I (12.30 ± 4.19) and group II (11.29 ± 4.57). DBP response to sustained handgrip was lowest in group II (5.88 ± 6.59) than group I (8.06± 7.77) and III (9.45 ± 9.90) but it was insignificant. Cold pressor test SBP response was higher in group I and DBP response was higher in group II. The parasympathetic response in the form of Valsalva maneuver and DBD were normal in all three groups but were higher in group I than other groups. Negative correlation was found between age and all the parameters except DBP response to SHG but it was statistically insignificant. Conclusion: Decline in autonomic functions cannot be solely associated with ageing but can be associated with other contributing factors.
Authors and Affiliations
Yunati MS
Keywords
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