Drug Resistance in Uropathogenic Escherichia coli among Patients with Urinary Tract Infection in a Tertiary Care Hospital
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 8
Abstract
The increasing prevalence of antibiotic resistance is a major health problem worldwide therefore World Health Organisation (WHO) has recognized the importance of studying the emergence and, the determinants of resistance and the need for strategies for its control. UTI are a common cause of morbidity in women. The majority of cases involve only the lower urinary tract and the most common pathogen is Ecoli. To study drug resistance in uropathogenic Ecoli among patients of urinary tract infections (UTI) in a tertiary care hospital. Mid-stream urine samples from patients clinically suspected to have UTI attending our hospital was collected after proper instructions. Antibiotic sensitivity will be done using modified Kirby-Bauer disk diffusion method. There were 65 females and 35 males with mean age of 49.79yrs. 54% had a colony count of 105cfu/ml; 104cfu/ml in 24% of the cases and in 22% of the samples, the colony count was 103cfu/ml. high degree of sensitivity was shown to amikacin (77%) and low sensitivity to ampicillin (20%). Among the the 100 uropathogenic Ecoli samples isolated in our study maximum of them (60%) were ESBL producers which owes for the resistance to various antibiotics. Most of the patients had diabetes mellitus as risk factor for UTI (84%). Urinary tract infection is an important problem in the community. Most of these infections are been landing on in a uncomplicated infection because of rising prevalence of antibiotic resistance by the organism causing it. Many community based survelliance studies are required to determine the specific risk factors associated with acquisition and to establish preventive measures within the community.
Authors and Affiliations
Dr. Bhushan C Shetty, Dr. M. V Kalasurmath
Keywords
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