DRY EMULSION: A PROMISING DOSAGE FORM TO DELIVER LIPOPHILIC DRUG MOLECULES WITH IMPROVED STABILITY AND EFFECTIVENESS
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2013, Vol 1, Issue 1
Abstract
Liquid emulsions have distinct advantages over the other oral dosage forms by improving the bio availability and by reducing the side effects, but the number of emulsion formulations currently in use are few compared with other oral dosage forms due to lack of physical - chemical and compliance problems. To overcome these problems dry emulsions are prepared. Dry emulsions are prepared by drying liquid o/w emulsions containing a solid carrier in the aqueous phase. The solid carrier provides the dry emulsions with bulk and mass. Dry emulsions are lipid based powder formulations from which an O/W emulsion can be reconstituted in-vivo or in-vitro. Dry emulsions can be prepared by spray drying, lyophilization and rotary evaporation. Unfortunately the dry emulsions were cohesive powders. The cohesiveness was reduced by addition of sucrose.
Authors and Affiliations
Haritha M, Priyanka M, Abeda Aqther, Neeharika R, Pragati Kumar
Keywords
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