Effect of body temperature on residual neuromuscular blockade of intermediate-acting neuromuscular blocking agents
Journal Title: Ege Tıp Dergisi - Year 2016, Vol 55, Issue 2
Abstract
Aim: Aim of this study was to compare the rates of residual neuromuscular block in patients at different postoperative body temperatures. We also investigated incidence of early postoperative residual neuromuscular block with intermediate acting neuromuscular blocking agents and the factors affecting early postoperative residual neuromuscular block with intermediate acting neuromuscular blocking agents. Material and Methods: Two hundred and sixty-eight patients who underwent surgery under general anesthesia were enrolled in this study. Patients were monitored with an acceleromyograph from the moment of admission to post anesthesia care unit. In addition to Train of Four (TOF) measurements, patients' clinical findings (tongue depressor test, hand squeezing, existence of diplopia, ability to swallow, ability to lift head and legs for 5 seconds) were monitored and recorded. Patients body temperatures are measured with a tympanic thermometer and residual neuromuscular block at different body temperatures were compared. Results: The incidence of residual neuromuscular block was 48.9%. Univariate analysis of the data showed that surgical duration, maintenance dose administration, administration of reversal agent and body temperature were significantly relevant with residual neuromuscular block. There weren't any statistically significant difference between TOF values of patients with body temperatures lower or higher than 35ºC who were administered either one of the 3 neuromuscular blocking agents utilized in this study. Conclusion: We conclude that choice of intermediate acting neuromuscular blocking agent has no influence on residual neuromuscular block in patients with both intraoperative and postoperative mild hypothermia.
Authors and Affiliations
Sermin Karaarslan, Mustafa Gönüllü, Zeki Tuncel Tekgül, Ergin Alaygut, Yücel Karaman
Keywords
Related Articles
- EP ID EP340432
- DOI 10.19161/etd.344183
- Views 123
- Downloads 0
Comparison of the results of ultrasonography-guided percutaneous liver mass biopsy performed with 18 and 20 gauge needles
Aim: To evaluate the role of using 18 Gauge (G) and 20G sharp needles in ultrasonography (US)-guided percutaneous liver mass biopsy regarding diagnostic success and efficacy is aimed. Materials and Methods: Sixty patient...
Henoch-Schonlein purpura: A case with involvement of the penis and scrotum
Henoch-Schönlein purpura (HSP), characterized by non-thrombocytopenic purpura accompanied by arthritis / arthralgia, gastrointestinal and genitourinary system involvement is the most common vasculitis in childhood. In ca...
Transcriptional networks and cell signals in embryonic development
The formation of the three lineages of the mouse blastocyst provides an important model system to study behavior of cells in the early stage of the development process, internal and external factors which play a role in...
Anti-TNF therapy-induced autoimmunity
Aim: Anti-TNF therapy has recently emerged as an effective therapy for treating rheumatic diseases. With this increasing use and longer follow-up periods of treatment, various adverse effects are emerging. These adverse...
Adrenal insufficiency in a 19-year-old male patient admitted with fatigue
Adrenal insufficiency is quite rare and 70-90% of cases develop as a result of autoimmune adrenalitis. The rest may be the result of infections, metastasis, adrenal haemorrhage / infarct or adverse effects of drugs. Prim...