Effect of extracts of lichens of different solvent races against clinically infectious bacteria
Journal Title: Medpulse International Journal of Microbiology - Year 2019, Vol 10, Issue 1
Abstract
Background: Lichens are well-known prolific sources of biologically active natural products. They are symbiotic organisms of fungi and algae that synthesize numerous metabolites called the “lichen substances”, which comprise aliphatic, cycloaliphatic, aromatic, and terpenic compounds. Lichens are good sources of biologically active secondary metabolites and have been used as medicine in treating wounds, stomach diseases, and whooping cough worldwide Bactericidal activity of crude extracts from lichens Usnea perplexans Stirton, Usnea spinocula Stirton, Usnea subsordiata Stirton, Ramalina conduplicans Vainio, Roccella montagnei Bel emend, Aswath were screened against pathogenic strains like gram negative bacteria such as Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and gram positive bacteria such as Staphylococcus aureus, Enterococci faecalis and Bacillus cereus. Aims and Objectives: To find out the Minimal inhibitory concentration (MIC) of the selected lichens against standard bacterial strains and to find out the Antibacterial activity of the selected lichen extracts Methods: The minimal inhibitory concentration of ethanol, methanol and acetone extracts of the selected lichens were determined against American type cell culture (ATCC) and Microbial type cell culture (MTCC) strains. All the three extracts of the selected lichens was potent in inhibiting bacterial growth which was tested by agar well diffusion method. Results: All the extracts exhibited bactericidal activity against the infectious sources and were dependent on the strain and solvent used. Conclusion: Lichen extracts of different solvent races showed significant antibacterial activity related to the tested gram positive and gram negative bacteria.
Authors and Affiliations
N S Ravichandran, Daya Pauline S, Vishnu G Ashok
Keywords
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- EP ID EP590564
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