EFFECT OF POSTMENOPAUSAL STATUS ON SERUM LIPIDS PROFILE AND URIC ACID IN SUDANESE FEMALES FROM THE GENERAL POPULATION
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 3
Abstract
BACKGROUND: Previous data suggest possible effects of postmenopause on serum lipids profile and uric acid which are established risk factors for cardiovascular system. AIM: to evaluate the changes that may occur on serum lipids profile and uric acid measurements in postmenopausal Sudanese women. MATERIALS AND METHODS The study involved 150 females. The studies subjects were grouped according to their menstrual status to women at age of menarche (75 women) their age ranged between (45 – 90 years, mean of 59.1), and women at age after menopause (75 women) aged between (25 – 49 years, mean 35.9). Following at least 12 hours fasting, serum total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), and uric acid were measured. RESULTS: lipids measurements were significantly different in both groups; HDL-cholesterol was significantly less in postmenopausal women (M±SD = 45.2±13.76 mg/dl) compared to women at age of menarche (M±SD = 51.8±14.9 mg/dl, P = 0.032). TC, LDL, and UA concentrations are significantly increased in postmenopausal women (171±19.6 mg/dl, 120.5±19 mg/dl and 5.0±0.8 mg/dl) compared with women at age of menarche (149.2±25.7 mg/dl and 94.7±10.1 mg/dl, and 3.66±0.7, P = 0.000, 0.002, and 0.001 respectively). CONCLUSION: two possible cardiovascular risk factors may present in postmenopausal women hyperlipidaemia and increased uric acid, so screening is necessary to women at this age.
Authors and Affiliations
Abeer Bashir| Department of Clinical chemistry, Faculty of Medical Laboratory Sciences, Sudan International University- Sudan, AbdElkarim A. Abdrabo*| Department of Clinical chemistry, Faculty of Medical Laboratory Sciences, Al Neelain University - Sudan
Keywords
Related Articles
- EP ID EP1800
- DOI -
- Views 359
- Downloads 25
INVITRO ANTIOXIDANT ACTIVITY AND HPTLC ANALYSIS OF WITHANIA SOMNIFERA
Withania somnifera is a well known medicinal plant having wide range of medicinal properties. HAEWS, MEWS and AEWS were comparatively standardized for the content of Withanolide D by HPTLC. All the samples were screened...
Spherical Crystallization: A Novel Particle Design Technique
Oral route is the most important route of drug administration. In this route, the solid dosage form specially tablets, are the first choice of patient but due to unfavorable physical and mechanical properties their formu...
EVALUATION OF PRESCRIBED CARDIOVASCULAR DRUGS MARKETED BY VARIOUS PHARMACEUTICAL COMPANIES OF BANGLADESH
Cardiovascular drugs encompass a large number of prescription medications that are used to control heart disease. It is a complicated group of drugs with many being used for multiple heart conditions. The main objective...
EVALUATION OF SOME BRANDS OF SHAMPOOS ACCORDING TO THE LIBYAN STANDARD SPECIFICATION
There are many brands of shampoos in Tripoli markets-Libya, available from different sources, locally and imported from other different countries. The aim of this work was to investigate whether such brands comply with...
RELEVANCE OF EPIGENOMICS IN THE MANAGEMENT OF CANCER
The recognizable proof of all epigenetic adjustments involved in gene expression is the succeeding stage for an improved comprehension of human biology in both typical and obsessive states. This field is implied as Epig...