Effect of thyme (Thymus Vulgaris L.) oil on some biochemical parameters of diabetic female rats
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 6
Abstract
The present study aimed to evaluate the influence of thyme oil on some biochemical parameters of diabetic female rats. Twenty four female rats divided into four groups each group contain six animals as following: the first group I (control group) was treated with (0.4mL/kg) of normal saline for two weeks, the second group II (diabetic group) was treated with alloxan (125 mg/kg), the third group III (thyme oil) was treated with (0.4mL/kg) of thyme oil for two weeks and the fourth group IV (diabetic-thyme oil group) was treated with alloxan (125 mg/kg) and then treated with (0.4 mL/kg) of thyme oil for two weeks. The results indicated a significant increase in the level of serum glucose, total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), very low density lipoprotein (VLDL), creatinin and uric acid in group (II) comparison with group (I). While, the level of high density lipoprotein (HDL) decreased significantly in group (II) comparison with group (I). There was a significant decrease (P<0.05) in the level of serum glucose, TC, TG, LDL, VLDL, creatinin and uric acid in group (IV) comparison with group (II). Also, the level of HDL increased significantly in group (IV) comparison with group (II).
Authors and Affiliations
Rasha J. Tuama
Keywords
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