Effects of addition of dexmedetomidine to bupivacaine on the block characteristics of brachial plexus block by supraclavicular approach
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1
Abstract
Background: Dexmedetomidine, a non-opioid adjuvant to neural blockade supposed to improve the quality of nerve blockade. This study intends to compare the effects of addition of dexmedetomidine as an adjutant to bupivacaine for supraclavicular brachial plexus block. Methods: A prospective, double blinded, randomized control study was conducted on 60 adult patients scheduled to undergo elective upper limb orthopedic procedures under regional anaesthesia. The patients were divided into two groups by randomization. Group A patients received 30ml of 0.325% bupivacaine containing 0.3 ml of distilled water.Group B patients received 30ml of 0.325% bupivacaine containing 0.3 ml of dexmedetomidine (30 mcg). Onset of sensory, motor blockade, duration of sensory and motor blockade, duration of post-operative analgesia and adverse effects, if any, were observed. Results: Demographic profile between two groups of patients were comparable. Mean(SD) time of onset of sensory block and motor blockade between group A vs Group B were 10.37 ±2.86 vs 6.17±1.58, 15.93±2.30 vs 11.10±2.12 . Mean (SD) duration of sensory and motor blockade between group A vs Group B were 240.03 ±39.84vs 824.03± 38.05, 208.43± 33.47 vs 779.87± 32.91 . Mean (SD) Duration of post-operative analgesia was 271.60±37.92 vs 857.10 ±37.83 .Statistically highly significant difference was observed between Group A and Group B patients in terms of onset of sensory, motor blockade, duration of sensory, motor blockade and duration of post-operative analgesia (p<0.001) Conclusion: Dexmedetomidine added as an adjuvant to bupivacaine for supraclavicular brachial plexus block has superior quality of sensory and motor blockade with prolonged postoperative analgesia with negligible adverse events.
Authors and Affiliations
C S Prakash, S Vigneshwaran
Keywords
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- EP ID EP440506
- DOI 10.26611/1015814
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