Effects of addition of dexmedetomidine to bupivacaine on the block characteristics of brachial plexus block by supraclavicular approach

Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1

Abstract

Background: Dexmedetomidine, a non-opioid adjuvant to neural blockade supposed to improve the quality of nerve blockade. This study intends to compare the effects of addition of dexmedetomidine as an adjutant to bupivacaine for supraclavicular brachial plexus block. Methods: A prospective, double blinded, randomized control study was conducted on 60 adult patients scheduled to undergo elective upper limb orthopedic procedures under regional anaesthesia. The patients were divided into two groups by randomization. Group A patients received 30ml of 0.325% bupivacaine containing 0.3 ml of distilled water.Group B patients received 30ml of 0.325% bupivacaine containing 0.3 ml of dexmedetomidine (30 mcg). Onset of sensory, motor blockade, duration of sensory and motor blockade, duration of post-operative analgesia and adverse effects, if any, were observed. Results: Demographic profile between two groups of patients were comparable. Mean(SD) time of onset of sensory block and motor blockade between group A vs Group B were 10.37 ±2.86 vs 6.17±1.58, 15.93±2.30 vs 11.10±2.12 . Mean (SD) duration of sensory and motor blockade between group A vs Group B were 240.03 ±39.84vs 824.03± 38.05, 208.43± 33.47 vs 779.87± 32.91 . Mean (SD) Duration of post-operative analgesia was 271.60±37.92 vs 857.10 ±37.83 .Statistically highly significant difference was observed between Group A and Group B patients in terms of onset of sensory, motor blockade, duration of sensory, motor blockade and duration of post-operative analgesia (p<0.001) Conclusion: Dexmedetomidine added as an adjuvant to bupivacaine for supraclavicular brachial plexus block has superior quality of sensory and motor blockade with prolonged postoperative analgesia with negligible adverse events.

Authors and Affiliations

C S Prakash, S Vigneshwaran

Keywords

Related Articles

Dexmedetomidine as epidural adjuvant to Ropivacaine in elective lower limb surgeries

Epidural adjuvants are used to prolong the action of local anesthetic agent so as to have prolongation of motor and sensory block. Dexmedetomidine a newer α2 agonistic agent with predominant affinity to α2receptor, α2:α1...

Comparison of low volume high concentration of local anesthetic with high volume low concentration local anesthetic for supraclavicular block

Regional anesthesia in form of brachial plexus block is a common and reliable mode of anesthesia for upper limb blocks. By virtue of anatomy of brachial plexus supraclavicular approach for brachial plexus is one of favou...

Clinical audit to evaluate the palliative care and pain relief practices in a tertiary care hospital

Background: Malignancy is one of the life limiting illnesses. Palliative care includes relief of physical as well as emotional, spiritual and social pain. Assessment and management of symptoms is likely to ensure follow...

Comparative study of ropivacaine with clonidine versus ropivacaine alone in supra clavicular brachial plexus block for upper limb surgery, study of 60 cases

Background: Supraclavicular brachial plexus block is most commonly preferred anaesthesia for upper limb orthopaedic surgeries. Various adjuvants to local anaesthetics were studied to prolong the duration of analgesia of...

Clonidine- An ideal premedicant for attenuation of haemodynamic side effects of intravenous Ketamine anaesthesia

Background: Using Ketamine as an anaesthetic agent is often associated with tachycardia and hypertension due to cardiostimulatory effects. Clonidine being an α2 agonist is supposed to be an ideal premedicant for it. Mate...

Download PDF file
  • EP ID EP440506
  • DOI 10.26611/1015814
  • Views 124
  • Downloads 0

How To Cite

C S Prakash, S Vigneshwaran (2017). Effects of addition of dexmedetomidine to bupivacaine on the block characteristics of brachial plexus block by supraclavicular approach. Medpulse International Journal of Anesthesiology, 8(1), 19-23. https://europub.co.uk/articles/-A-440506