EFFECTS OF AQUEOUS EXTRACT OF EUGENIA OPERCULATA ROXB. ON NORMAL AND STREPTOZOTOCIN INDUCED DIABETIC MICE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 12
Abstract
The aim of this study is to determine the antihyperglycemic properties of an aqueous extract of Eugenia operculata leaves on blood glucose and body weight of normal and Stz induced diabetic albino mice and also to determine its antimicrobial activity. Blood glucose levels of Stz treated mice were found to be declined sharply from 244.33 to147.33 mg/dL after oral feeding of extract at 200mg/kg b.w and from 174 to 140 at 100 mg/kg b.w on 15th day. The extract was potent against S.aureus, P.aeruginosa and B.subtilis with an inhibition zone of 39, 35, 18mm respectively. The MIC of extract against S.aureus and P.aeruginosa were 12.5 and 3.25mg/ml resp. Eugenia operculata leaves could be a potential source of antidiabetic and antimicrobial agents for drug formulation.
Authors and Affiliations
Romila Devi, P. B. Mazumder
Keywords
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