Efficacy Of Low Dose Aspirin In Reducing Deep Vein Thrombosis In Patients Of Lower Limb Fracture Waiting For Surgery
Journal Title: International Journal of Orthopaedics Traumatology & Surgical Sciences - Year 2016, Vol 2, Issue 0
Abstract
Background: Deep vein thrombosis is one of the most common complications in patients who have sustained skeletal injury. When given for antithrombotic prophylaxis in high risk medical or surgical patients, aspirin was shown to reduce the incidence of venous thrombo-embolism in clinical studies and meta-analyses. However, controversial recommendations have been released on the role of aspirin for the prevention of venous thrombo-embolism. Our study is to support the role of and to know the efficacy of aspirin in reducing DVT in patients of lower limb fracture. Material and methods: In our study cases were selected those who had fracture of lower limb and bed ridden and operation delayed due to any reason. All patients fulfilling the criteria for inclusion were registered and distributed in two groups randomly. One group receives 150 mg of aspirin and other receive placebo once a day from day of admission to 24 hours of surgery. Serial venous colour Doppler of bilateral lower limb was done. Results: Out of 108 patients 51 patients of group A received 150 mg aspirin, and 57 patients of group B received placebo. In serial venus colour doppler study 6 patients develop DVT in placebo group while no DVT were detected in aspirin group. Conclusion:- By this study we come to know that chemoprophylaxis with low dose aspirin in patient of lower limb fracture plays a definite roll in the prevention of DVT in these patients and can save them with this cheapest means.
Authors and Affiliations
Sameer Gupta, Manish Singh Rajpoot
Keywords
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