Etiopathological and management profile of Wilms tumour – A single centre experience
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 10
Abstract
Wilms tumour is the most common renal tumor of childhood that typically affects children under the age of 6 years.It is the subject of intense academic interest due to its occurrence in paediatric age group with significant mortality which has been significantly reduced with relapse free survival rates due to collaborative protocols like SIOP(international society of paediatric oncology) and COG(children’s oncology group).The study aimed to assess the various prognostic factors that determine the outcome of Wilms tumour,to analyze the prognostic value of histopathology and tumour staging in Wilms tumour and to identify the causes for early mortality. It is a retrospective and cross sectional study done in the Department of Paediatric surgery , Coimbatore Medical College, Coimbatore from December 2008 to December 2017. Hospital charts and surgical notes were reviewed and the results of 25 children with Wilms tumour were analyzed. Stage I tumours had 100% survival rate. The mortality rate was higher in Stage III and Stage IV tumours (more than 75%).The unfavorable histology group had 80% mortality rate. Higher mortality rate was observed in less than 24 months age group .Resectabilty of the tumour at the time of initial diagnosis has significant prognostic value .Tumour spillage and lymph nodal involvement are associated with early mortality and recurrent tumour.
Authors and Affiliations
R P Dharmendra, S Yogalakshmi, M Raghul
Keywords
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- EP ID EP406705
- DOI 10.9790/0853-1710104853.
- Views 63
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