Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 9
Abstract
Background: Doppler velocimetry studies of placental and fetal circulation can provide important information regarding fetal well-being providing an opportunity to improve fetal outcome. Aims and Objective: The aim of this study to evaluate the role of color Doppler velocimetry of the fetal middle cerebral artery (MCA) velocity waveforms, systolic/diastolic ratio (S/D), pulsatility index (PI), and resistance index (RI) in intrauterine growth restriction (IUGR) pregnancies in II and III trimesters. Materials and Methods: This was a cross-sectional study. The control and study groups were studied in II and III trimesters. They were first subjected to ultrasonography biometry and then to MCA Doppler sonography. The statistical analysis was performed by “unpaired” and “paired” t-test. Results: In both control and study groups, the values of S/D ratio, PI, and RI in MCA decline during II to III trimester. The values were lower in the study group as compared to the control group. Thus that the present study predicts were; (a) lower PI values were suggestive of fetal hypoxia, (b) The lower values are due to vasodilatation due to hypoxia to supply more blood to the brain to protect it from the damaging effects of hypoxia. Thus, the brain is spared from damage. Conclusion: Doppler can be considered as one of the important non-invasive techniques to assess the fetomaternal and uteroplacental circulations. The MCA indices were valuable for predicting the outcome of IUGR pregnancies.
Authors and Affiliations
Padmaja Rajey Desai, Sunita Milind Tiwale, Pandian Murugesan Devar, Rajey M Desai
Keywords
Related Articles
- EP ID EP291944
- DOI 10.5455/njppp.2017.7.0413325042017
- Views 82
- Downloads 0
Dynamics of the content of free amino acids in blood of patients during the long-term use of orthopedic dental metal prostheses
Background: The effect of materials for dental prostheses on the patient’s body remains one of the most relevant issues in orthopedic dentistry. The dentist, more often the orthopedist, has to deal with diseases arising...
Assignment-based learning of essential medicine list concepts among undergraduate medical students
Background: The concepts of essential medicines and rational drug therapy are necessary to be understood undergraduate students. Aims and Objectives: (i) To make the second MBBS students aware regarding essential medicin...
Analysis of the development of Hirschsprung-associated enterocolitis in children
Background: Hirschsprung disease (HD) - severe congenital anomaly of the colon, characterized by the violation of the innervation of the fragment, and even the entire department of the large intestine, is one of the lead...
Student perceptions on activity-based learning in physiology
Background: Concept building is very important for learning physiology. Active involvement of the students when a particular topic is being taught has been hypothesized to benefit the students to learn physiology effecti...
Innovation of dodol and stick milk and quality control of product based on microbial contaminant
Background: Innovations of traditional food such as dodol and sticks are to improve the quality and sale value products. The innovation of dodol and sticks are one way to change the cow’s milk to be food products. Aims a...