Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2017, Vol 7, Issue 9
Abstract
Background: Doppler velocimetry studies of placental and fetal circulation can provide important information regarding fetal well-being providing an opportunity to improve fetal outcome. Aims and Objective: The aim of this study to evaluate the role of color Doppler velocimetry of the fetal middle cerebral artery (MCA) velocity waveforms, systolic/diastolic ratio (S/D), pulsatility index (PI), and resistance index (RI) in intrauterine growth restriction (IUGR) pregnancies in II and III trimesters. Materials and Methods: This was a cross-sectional study. The control and study groups were studied in II and III trimesters. They were first subjected to ultrasonography biometry and then to MCA Doppler sonography. The statistical analysis was performed by “unpaired” and “paired” t-test. Results: In both control and study groups, the values of S/D ratio, PI, and RI in MCA decline during II to III trimester. The values were lower in the study group as compared to the control group. Thus that the present study predicts were; (a) lower PI values were suggestive of fetal hypoxia, (b) The lower values are due to vasodilatation due to hypoxia to supply more blood to the brain to protect it from the damaging effects of hypoxia. Thus, the brain is spared from damage. Conclusion: Doppler can be considered as one of the important non-invasive techniques to assess the fetomaternal and uteroplacental circulations. The MCA indices were valuable for predicting the outcome of IUGR pregnancies.
Authors and Affiliations
Padmaja Rajey Desai, Sunita Milind Tiwale, Pandian Murugesan Devar, Rajey M Desai
Keywords
Related Articles
- EP ID EP291944
- DOI 10.5455/njppp.2017.7.0413325042017
- Views 76
- Downloads 0
A comparative study of impact of obesity on maximum voluntary ventilation in young adult women
Background: Obesity has become a global epidemic. The prevalence and severity of obesity in young adult females are dramatically increasing worldwide. Along with other organs, respiratory system is also compromised. Obes...
Effect of total and central adiposity on the blood glucose level of Gujarati Indian adolescents
Background: There is an emerging epidemic of type 2 diabetes mellitus (DM) among children and adolescents due to increased prevalence of obesity. Indians have a genetic phenotype characterized by low b...
Prevalence of the musculoskeletal disorder among school teachers
Background: Musculoskeletal disorders (MSDs) represent one of the most common and important occupational health problems in working populations, being responsible for a substantial impact on the quality of life and incur...
Behavioral assessment of antidepressant activity of Memantine - a NMDA receptor antagonist in animal models: An experimental study
Background: Around 5–10% of patients on selective serotonin reuptake inhibitors discontinue therapy because of side effects. Therefore, research for newer antidepressants with greater effectiveness has to be explored. Ai...
A glimpse into the pathophysiology, mechanisms, and management of neuropathic pain
One of the most frequent problems in medical care is the management of patient presenting with chronic pain. Neuropathic pain is related to the injury or disorders affecting peripheral and central nervous systems...