Evaluation of Frozen Section Biopsy in Gynecological Neoplasms in Southern Odisha
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Abstract: Gynecologic cancers form a huge burden of morbidity and mortality around the world. Cancers of the female reproductive tract has a high incidence amongst Indian women. Frozen section is to provide rapid diagnosis to guide intra or perioperative patient’s management. This diagnostic procedure can reduce regret of doing incomplete surgery for malignant tumor or radical surgery for benign condition in a majority of patients. The importance lies in determining the nature of a lesion whether benign or malignant during surgery, assessment of resection margins, and demonstration of fat in tissues and preservation of enzymes /antigenic markers to assess the role of frozen section in analyzing gynecological neoplasms & to correlate with routine histopathology. The prospective study was conducted in the Department of Pathology with collaboration with Department of Obstetrics & Gynecology of MKCG Medical College & Hospital, Berhampur from 2012 to 2014. Eighty nine neoplastic lesions of female genital tract constituted the study group. Fresh unfixed specimens were received in the frozen section unit, were grossed in the unfixed state and 5 micron sections were prepared using the cryostat, stained with rapid H&E stain and evaluated immediately. The average turnaround time was 15 min. After definitive surgery routine histopathological evaluation of the specimen was performed and the results of both procedures were correlated. The site distributions of the cases were ovary (50), cervix (25) and rest 14 cases from other parts of female genital tract. Eighty three cases showed positive correlation (93.25%) and 6 cases showed negative correlation (6.74%). Frozen section is less time consuming, helping the surgeons for an on table decision for radical surgery, reduces repeated anesthetic need and ultimately reducing the patient’s anxiety for waiting for results.
Authors and Affiliations
Sanghamitra Sahoo, Atanu Kumar Bal, Debi Prasad Mishra, Samira Ku. Behera
Keywords
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