Evaluation of Frozen Section Biopsy in Gynecological Neoplasms in Southern Odisha
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Abstract: Gynecologic cancers form a huge burden of morbidity and mortality around the world. Cancers of the female reproductive tract has a high incidence amongst Indian women. Frozen section is to provide rapid diagnosis to guide intra or perioperative patient’s management. This diagnostic procedure can reduce regret of doing incomplete surgery for malignant tumor or radical surgery for benign condition in a majority of patients. The importance lies in determining the nature of a lesion whether benign or malignant during surgery, assessment of resection margins, and demonstration of fat in tissues and preservation of enzymes /antigenic markers to assess the role of frozen section in analyzing gynecological neoplasms & to correlate with routine histopathology. The prospective study was conducted in the Department of Pathology with collaboration with Department of Obstetrics & Gynecology of MKCG Medical College & Hospital, Berhampur from 2012 to 2014. Eighty nine neoplastic lesions of female genital tract constituted the study group. Fresh unfixed specimens were received in the frozen section unit, were grossed in the unfixed state and 5 micron sections were prepared using the cryostat, stained with rapid H&E stain and evaluated immediately. The average turnaround time was 15 min. After definitive surgery routine histopathological evaluation of the specimen was performed and the results of both procedures were correlated. The site distributions of the cases were ovary (50), cervix (25) and rest 14 cases from other parts of female genital tract. Eighty three cases showed positive correlation (93.25%) and 6 cases showed negative correlation (6.74%). Frozen section is less time consuming, helping the surgeons for an on table decision for radical surgery, reduces repeated anesthetic need and ultimately reducing the patient’s anxiety for waiting for results.
Authors and Affiliations
Sanghamitra Sahoo, Atanu Kumar Bal, Debi Prasad Mishra, Samira Ku. Behera
Keywords
Related Articles
- EP ID EP474681
- DOI -
- Views 93
- Downloads 0
Thyroid Dysfunction in Pregnancy and Preeclampsia
Pre -eclampsia is a leading cause of maternal & foetal morbidity & mortality worldwide. There is a state of hypothyroxinemia in normal pregnancy, it is more pronounced in preeclampsia. Moreover hypothyroidism has been li...
Spectrum of Endometrial Histopathology in Women Presenting with Abnormal Uterine Bleeding
Abnormal uterine bleeding is the common presenting complains in the Gynaecology outpatient department in all age groups. Histopathological evaluation of the endometrial samples plays a significant role in the diagnosis o...
A Comparative Study of Efficacy of Dapsone and Corticosteroids for the Treatment of Lichen Planus
Lichen Planus is defined as papulo-squamous disorder of unknown etiology characterised by itchy papules over the flexors of the body. Lichen planus presents as pruritic, polygonal, purplish, plane topped papules or plaqu...
Seroprevalence of C - Reactive Protein in Rheumatoid Arthritis Cases: A Retrospective Study in a Tertiary Care Hospital in South India
Abstract: Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune inflammatory disease that affects mainly the small joints of the hands and feet. It is one of the most common inflammatory joint diseases that compro...
A Study into the Maternal Sociodemographic Factors and Its Association with Birth Defects
A birth defect is described as a structural of functional deformity which is present since birth. Birth defects accounts for a significant cause of infant mortality and morbidity that has a formidable impact in low resou...