Evaluation of wound healing activity of hydroalcoholic extract of vetiveria ziznoides roots in wistar albino rats
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2018, Vol 7, Issue 1
Abstract
Background Wounds are the common skin disorders. It can occur by various methods. Agents having wound healing activity have wide therapeutic uses. The present study was planned to evaluate wound healing activity of hydroalcoholic extract of Vetiveria ziznoides roots in Wistar Albino rats Materials and Methods This study was done in the department of Pharmacology, SMIMS. Total 24 rats were divided in to four groups each of 6 rats. G-I: Control, G-II: HAEV.Zroot (75 mg/kg), G-III: HAEV.Zroot (150 mg/kg) and G-IV: HAEV.Zroot (300 mg/kg). 6 cm length of incision was made at para vertebral palace. Rats were given test drugs one week before incision made and one week after incision. Control group treated with distilled water. On 15th day tensile strength was measured. Results Significant difference was observed in the tensile strength with high dose of test drug compared to low dose and control group. Conclusion In conclusion, pre-administration of V.Z root increased wound healing compared to control group. Further studies required to find the mechanism of action.
Authors and Affiliations
Sarath Babu K
Keywords
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