Formulation and evaluation of mucoadhesive microspheres for gastro retentive delivery of Famotidine hydrochloride
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 3
Abstract
The purpose of the research was to develop mucoadhesive gastro retentive drug delivery system containing Famotidine hydrochloride. The mucoadhesive microspheres were prepared by using varying concentrations of sodium alginate and egg albumin. The technique used in the preparation of microspheres was Ion gelation and Thermal cross linking method. The polymers are biodegradable. In-vitro drug release studies were conducted along with other physical parameters like particle size determination, surface morphology, mucoadhesion and drug entrapment efficiency.
Authors and Affiliations
K. Divya, B. Sailaja, K. Y. Guru Swamy, G. Mahesh, V. Ravi Kumar, B. Renuka, B. Nagendra Babu
Keywords
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