Invitro anti-arthritic, anti-inflammatory and anti-oxidant activity of Cissus quadrangularis linn
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2015, Vol 3, Issue 1
Abstract
The present investigation deals with the study of in vitro anti-arthritic activity by inhibition of protein denaturation method, anti- inflammatory by HRBC membrane stabilization method and anti-oxidant activity by DPPH method. Cissus quadrangularis Linn plant is a perennial tendril climber with quadrangular stem. It is used in the treatment of gout, syphilis, stomach ache, regularize menstrual cycle, antimicrobial activity and piles in Ayurvedic medicine and traditionally used for bone fracture. The air dried powder of Cissus quadrangularis Linn (aerial parts) were extracted using Soxhlet apparatus with ethanol as solvent. The extracts were concentrated under reduced pressure. The activities were carried out using the following concentration (31.2, 62.5, 125, 250, 500, 1000, 2000 µg/ml). It has significant in vitro anti-arthritic, antioxidant and antiinflammatory activity. The activity may be due to presence of chemical profile such as phenolic acid, flavonoid (leuteotin) and β-sitosterol. The results of the study have implications in the use of Cissus quadrangularis Linnas anti-arthritic, anti-inflammatory and antioxidant in several applications requiring these properties.
Authors and Affiliations
Gopinathan. N, Harish. G, Ashwin Kumar. G, Chitra. K and Umamaheswara Reddy. C
Keywords
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