Phytochemical screening, antiplatelet activity of Carica papaya leaf extract
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2016, Vol 4, Issue 3
Abstract
Carica papaya is belonging to family Caricaceae and it commonly known as papaya. Carica papaya leaves contain chemical constituents like carpine, psedo carpain, and dehydrocarpine I and II, carposide, vitamin C and vitamin E. Leaves of C. papaya used to Increase appetite, Ease menstrual pain, Meat tenderizer, Relieve nausea, in dengue fever. In the present study Carica papaya leaves extracts are prepared with methanol and water by soxhalation, the extracts are investigated for Phytochemicals and studied for invitro anti platelet activity by adrenaline induced platelet aggregation and calcium chloride induced platelet aggregation models. Both methanol and aqueous extracts are shown dose dependent platelet aggregation inhibition. More over Methanol extract shown good inhibition of platelet aggregation (65.63%) & (66.32%) than the aqueous extract (51.39%) & (62.85%) with 300µg/ml concentration than the control group, Aspirin is used as standard drug with 100μg/ml concentration and it showed inhibitory of Platelet aggregation (68.40%) & (68.68%) for both adrenaline induced and calcium chloride induce models simultaneously.
Authors and Affiliations
Narayanarao Alla, Satyanarayana T, Shara T, Naresh B, Nagaraju M, Himabindu J, Reshma Md
Keywords
Related Articles
- EP ID EP33388
- DOI -
- Views 301
- Downloads 0
Novel challenges of stem cell therapy in neurodegenerative disorders
Neurodegenerative diseases are characterized by progressive dysfunction, loss & death of neurons. In recent years, neurons and glial cells have been successfully generated from stem cells, by this from stem cell brain...
Influence of Genetic factor on Dental Caries
Caries remains the most prevalent non-contagious infectious disease in humans. Dental caries is a multi factorial infectious disease, with many contributory environmental factors, there is also strong evidence for a ge...
Isolation and identification of Azospirillum isolates from different paddy fields of North Bengal
Samples of rhizosphere soil, non-rhizosphere soil and roots of rice plants were collected from the particular locations of the 3 districts (Bogra, Naowgaon and Dinajpur) of North Bengal. Twenty different colonies of Az...
Phytochemical and anti diarrhoeal activity of Hippocratea africana roots
Diarrhoea is a condition that involves frequent passing of loose or watery stools. According to the Who, approximately 3.5million deaths each year are attributable to diarrhoea. Medicinal plants have been used as tradi...
Evaluation of hypo lipidemic and antioxident properties of methanolic extract of leaves of Tectona grandis linn on Mithionine induced model in Wister albino rats
The Methanolic extract of Tectona grandis leaves was subjected to phytochemical screening to find the chemical constituents present. The extract revealed the presence of carbohydrates, alkaloids, phytosterols, proteins...