Genomics of Acetylcholinesterase (AChE) enzyme and its related RNA content in the brain of Channa striata
Journal Title: IOSR Journal of Biotechnology and Biochemistry (IOSR-JBB - Year 2018, Vol 4, Issue 2
Abstract
Inhibition of acetylcholinesterase (AChE), the metabolizing enzyme of acetylcholine is evolving as the most important therapeutic target for development of cognitive enhancers. However, AChE activity in brain has not been properly evaluated on the basis of sex. In the present study, AChE expression was investigated in different brain areas of cerebrum and cerebellum in male and female chana striata. On comparing male and female genders, increased AChE activity was seen in cerebrum and cerebellum of female chana striata. However, no significant change in AChE activity was found between cerebrum and cerebellum within the same male and female. Thus it appears that sex alters AChE activity in different brain regions (G4 isoform) that may vary in male and female. Sequence analysis revealed that highest divergence was found in between male cerebrum and female cerebrum (6.0) and least divergence was found in between male cerebellum and female cerebellum (3.2) with control AChE NM_EF534897.
Authors and Affiliations
B Ramesh, PRK Bhargav, N Vimala devi
Keywords
Related Articles
- EP ID EP415060
- DOI 10.9790/264X-0402011220.
- Views 143
- Downloads 0
Antibiofilm effects of Adhatoda Vasica Nees. extracts in comparison with commercial vasicine on Streptococcus Pneumoniae
Medicinal plants like Adhatoda vasica Nees. are used traditionally in Tripura to cure pneumonia, cough and cold. Pneumonia is a lung infection with cough, fever and hard time breathing. Pneumonia is mainly caused by bact...
Comparison between Different Components of Some Available Hardwood and Softwood in Bangladesh
This research was conducted to examine comparison between hardwood and softwood components. Cellulose, hemicellulose and lignin are major constituents for both hardwood and softwood. Depending on these constituents wood’...
Microbial Production of Silver Nanoparticles (Agnps) By Some Bacterial Isolates
The five bacterial strains viz. Brevibacillus centrosporus DSM8445T, Brevibacillus invocatus NCIMB13772T, Brevibacillus choshinensis DSM8552T, Brevibacillus panacihumi DCY35 and Brevibacillus levickii LKG22481were screen...
Evaluation of Venous Blood as a Specimen of Choice in the Monitoring of Acid-Base Metabolic Disorders
Acid-base metabolic disorders are conditions that alter the normal body physiology that regulate the pH of blood in order to maintain normal biochemical functions. Maintenance of a constant pH is important for enzyme fun...
Isolation of Host Specific Bacteriophages against Salmonella and Methicillin Resistant Staphylococcus aureus (MRSA) From Hospital Waste Water
Worldwide emergence of new resistance mechanisms in constantly increasing infections of Multidrug Resistance (MDR) bacteria (such as Methicillin resistant Staphylococcus aureus (MRSA) and Salmonella) is generating a majo...