GRADE OF ARTERIAL HYPERTENSION SEVERITY IN PATIENTS WITH 2 TYPE DIABETES MELLITUS AND ITS INTERACTION WITH ADIPOPOCYTOKINE MEDIATORS, CARBOHYDRATE AND LIPID METABOLISM
Journal Title: Science Review - Year 2018, Vol 3, Issue 1
Abstract
The study describes the dynamics of parameters of carbohydrate and lipid metabolism, together with the activity of adipocytokine mediators, namely apelin-12 and obestatin, in patients with type 2 diabetes depending on the severity of arterial hypertension. In patients with arterial hypertension in combination with type 2 diabetes, there are synergistic attempts of apelin-12 and obestatin for normalizing blood pressure level, however, the concentration of these markers is inadequate for existing needs. The discrepancy between the levels of apelin-12 and obestatin in the activity of the renin-angiotensin-aldosterone system is accompanied by an increase in blood pressure of more than 180/100 mm Hg. in patients with type 2 diabetes mellitus.
Authors and Affiliations
O. S. Tabachenko, P. Kravchun, M. I. Kozhyn, Yu. O. Kovaleva, S. O. Krapivko
Keywords
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- EP ID EP415396
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