Hemodynamic changes and post-operative complications with use of caudal bupivacaine and bupivacaine-dexmedetomidine combination for post-operative analgesia

Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 5, Issue 1

Abstract

Background: Caudal anaesthesia is a commonly performed regional block in children for abdominal and lower limb surgeries. The use of adjuncts like Dexmedetomidine can effectively help in reduction of the dose and an increase in duration of action of the local anaesthetic agent like bupivacaine. Aim: To study addition of Dexmedetomidine to bupivacaine with regards to hemodynamic changes and post-operative complications. Material and Methods: A total of 60 patients of 2-10 years of age posted for routine infraumbilical surgerieswere randomly divided in to two groups. Group A- (Control group) received 0.25% Bupivacaine. Group B - (Study group) received 0.25% Bupivacaine + 1μg/kg Dexmedetomidine. Haemodynamic parameters in the form of pulse rate, blood pressure, SpO2, respiratory rate were observed. Results: The difference between the two groups for change in mean arterial pressure was statistically significant, but the patients were haemdynamically stable. Two patients from group A and one patient from group B had vomiting in the postoperative period. While two patients from both group A and group B complained of failure to pass urine at 6 hrs. Conclusion: The addition of dexmedetomidine in the dose of 1μg/kg to 0.25% bupivacaine for caudal blockade significantly prolongs the duration of analgesia without any significant hemodynamic changes and is safe for use in paediatric patients.

Authors and Affiliations

Attar Tausif, Kamble Raviraj, Agrawal Pushpa, Kulkarni Vaishnavi

Keywords

Related Articles

Diagnostic value of different screening tests for predicting difficult intubation

Aims: The aim of current study was to compare the diagnostic value of different screening test in predicting difficult intubation. Settings and Design: Hospital based observational cross sectional study Methods and Mater...

Effect of oral pregabalin premedication on perioperative haemodynamic response and post operative analgesic requirement for patients undergoing laparoscopic cholecystectomy

Background and Aims: Laparoscopic cholecystectomy was introduced by Phillipe Mouret in 1987. In comparison with open procedures, laparoscopy is characterized by better maintenance ofhomeostasis and reduced postoperative...

Comparison of I-gel versus proseal laryngeal mask airway (PLMA) for elective surgical elective surgical procedures

Background:Securing airway of patient during surgery is one of the most important responsibility of anesthesiologist.Though Endotracheal Tube is gold standard for securing airway during general anesthesia, various suprag...

A comparative study of esmolol versus dexmedetomidine in attenuation of cardiovascular response following laryngoscopy

Objectives: To compare the safety and efficacy of esmolol versus dexmedetomidine in attenuation of cardiovascular response to laryngoscopy. Study design: Randomized controlled clinical trial. Place and duration of study:...

Comparative study on the effect of addition of potassium chloride to bupivacaine on the onset time and duration of inter scalene block

Background: The interscalene block is a more established technique and has been used routinely for shoulder surgery. It is also more associated with well known, but short-lived, side effects than the supraclavicular tech...

Download PDF file
  • EP ID EP452963
  • DOI 10.26611/1015513
  • Views 122
  • Downloads 0

How To Cite

Attar Tausif, Kamble Raviraj, Agrawal Pushpa, Kulkarni Vaishnavi (2018). Hemodynamic changes and post-operative complications with use of caudal bupivacaine and bupivacaine-dexmedetomidine combination for post-operative analgesia. Medpulse International Journal of Anesthesiology, 5(1), 11-15. https://europub.co.uk/articles/-A-452963