Hemodynamic variables and side effects of 0.75% preservative free Ropivacaine for lower abdominal surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 7, Issue 2
Abstract
Bupivacaine has been shown to have selective cardiac effects related to the slow rate at which it dissociates from the sodium channel.4, 13 An important aspects of this toxicity is that it involves a significant degree of stereo specificity, with the ‘S’–isomer showing significantly less cardiotoxic effect. After institutional ethical committee approval and after informed consent of the patients, this study was undertaken on 60 patients of either sex, aged between 20 to 60 years belonging to ASA physical status grade I and II , scheduled for elective lower abdominal surgery. There was 10% decrease in Heart rate from the base line value and the maximum drop in Heart rate occurred at mean time of 26.08 ± 4.22 minutes from the time of injecting study drug in to the epidural space. No patients had bradycardia throughout the procedure. Side effects were very minimal in the present study.
Authors and Affiliations
A S Bala Sundar, Santosh Kumar, M Shivashankar
Keywords
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