Hyperleptinemia as One of the Factors for Renal Dysfunction in Patients with Hypothyroidism
Journal Title: Міжнародний ендокринологічний журнал - Year 2014, Vol 6, Issue 62
Abstract
In order to study the features of renal function in patients with hypothyroidism we have examined 132 patients with primary hypothyroidism. The results showed that in patients with overt hypothyroidism there is renal dysfunction manifested by increased serum creatinine level and decreased glomerular filtration rate, the development and progression of which is facilitated by the presence of risk factors in patients — hyperleptinemia, dyslipidemia, overweight and abdominal obesity. It is stated that more significant indicators of dyslipidemia were associated with the greatest manifestations of abdominal obesity in terms of waist circumference (96.58 ± 1.70 cm and 98.73 ± 3.35 cm), as well as greater body mass index.
Authors and Affiliations
O. M. Didushko
Treatment with Glucagon-Like Peptide-1 Analogues — a Breakthrough in Diabetes Mellitus Type 2 Therapy
The paper analyzes the data of modern scientific literature on the new class of drugs that restore the effect of glucagon-like peptide-1 (GLP-1). According to modern concepts, the pathophysio-logical mechanisms of therap...
Evaluating the informativity and specificity of diagnostic criteria for primary screening for acromegaly
Background. The most effective method for early diagnosis of any disease, and especially such rare as acromegaly, is considered to be population screening in high-risk groups, the introduction of which in Ukraine require...
Expression of Steroid Hormone Receptors of the Cervix in Cervical Intraepithelial Neoplasia Associated with Human Papillomavirus Infection in Infertile Women
The article presents the results of immunohistochemical study of estrogen and progesterone receptors of the cervix in cervical intraepithelial neoplasia (CIN) associated with human papillomavirus infection (HPI) in 157 w...
Changes of Cytokine Level in Patients with Hypertension and Obesity, Depending on the Duration of the Disease
Interleukins (IL) 2, 6, 10, and C-reactive protein are crucial in arterial hypertension with obesity. Background. To identify the characteristics of inflammatory markers in patients with arterial hypertension and obesity...
Analysis of Indicators of Diabetes Care Quality in the World and Ways to Optimize the Evaluation and Monitoring of Diabetes Care Quality in Ukraine
Control and monitoring of diabetes care quality — a strategic goal of public health service in each country. The objective of the study — to analyze indicators of diabetes care quality around the world and their possible...